To develop and validate a machine learning framework for the classification of distinct seizure onset patterns using intracranial EEG (iEEG) recordings in a non-human primate (NHP) model of penicillin-induced seizures.iEEG data were collected from si...
How does genomic information unfold, to give rise to self-constructing living organisms with problem-solving capacities at all levels of organization? We review recent progress that unifies work in developmental genetics and machine learning (ML) to ...
Low reticuloruminal pH (rpH) for a prolonged period could lead to SARA. This disease negatively affects cow health and is associated with monetary losses for the dairy industry. The aim of this study was to predict rpH and SARA separately using diffe...
ACS biomaterials science & engineering
Jun 9, 2025
Stem cells have a considerable role to play in future biomedical breakthroughs due to their therapeutic potential. As stem cells may be studied in a variety of different applications, a "one size fits all" approach to the stem cell culture substrate ...
Chronic kidney disease (CKD) remains a pressing global health issue with limited therapeutic options. The loss of nephrons is a crucial pathological change driving CKD progression, influenced by diverse programmed cell death (PCD) pathways, yet the p...
BioEssays : news and reviews in molecular, cellular and developmental biology
Jun 8, 2025
Organismal evolution is a process of discovering better-fitting phenotypes through trial and error across generations. This iterative process resembles learning processes, an analogy recognized since the 1950s. Recognizing this parallel suggests that...
The increasing prevalence of central nervous system (CNS) disorders has imposed a significant social and economic burden on healthcare systems. The blood-brain barrier (BBB) presents a major challenge for effective drug delivery to the brain, hinderi...
The concept of "code" connotes different meanings, intentions, and formalizations. From mathematics and computer sciences to psychology and culture, the term becomes less formal, more diverse, and sometimes appears ambiguous. In biology a growing num...
ETHNOPHARMACOLOGICAL RELEVANCE: Angong Niuhuang Pills (AGNHP), a famous Chinese medicine compound preparation, is widely used to treat stroke and other brain disorders. However, owing to the complexity of herbal components and diversity of production...
Regulatory toxicology and pharmacology : RTP
Jun 6, 2025
The toxicity of nanomaterials(NMs) is closely tied to their physicochemical properties, such as size, shape, surface chemistry, stability in biological medium, and state of agglomeration as well to their uptake by cells. Key deficiencies in standardi...
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