AIMC Topic: Anti-Arrhythmia Agents

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Automated Process for Monitoring of Amiodarone Treatment: Development and Evaluation.

Journal of medical Internet research
BACKGROUND: Amiodarone treatment requires repeated laboratory evaluations of thyroid and liver function due to potential side effects. Robotic process automation uses software robots to automate repetitive and routine tasks, and their use may be exte...

Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial.

Nature medicine
Although pulmonary vein isolation (PVI) has become the cornerstone ablation procedure for atrial fibrillation (AF), the optimal ablation procedure for persistent and long-standing persistent AF remains elusive. Targeting spatio-temporal electrogram d...

A python approach for prediction of physicochemical properties of anti-arrhythmia drugs using topological descriptors.

Scientific reports
In recent years, machine learning has gained substantial attention for its ability to predict complex chemical and biological properties, including those of pharmaceutical compounds. This study proposes a machine learning-based quantitative structure...

Erroneous electrocardiographic interpretations and its clinical implications.

Journal of cardiovascular electrophysiology
INTRODUCTION: The advancement of artificial intelligence (AI) has aided clinicians in the interpretation of electrocardiograms (ECGs) serving as an essential tool to provide rapid triage and care. However, in some cases, AI can misinterpret an ECG an...

Applications of machine learning in decision analysis for dose management for dofetilide.

PloS one
BACKGROUND: Initiation of the antiarrhythmic medication dofetilide requires an FDA-mandated 3 days of telemetry monitoring due to heightened risk of toxicity within this time period. Although a recommended dose management algorithm for dofetilide exi...

Improvement of Adequate Digoxin Dosage: An Application of Machine Learning Approach.

Journal of healthcare engineering
Digoxin is a high-alert medication because of its narrow therapeutic range and high drug-to-drug interactions (DDIs). Approximately 50% of digoxin toxicity cases are preventable, which motivated us to improve the treatment outcomes of digoxin. The ob...

Traditional Chinese Medicine for Anti-Arrhythmias: Mechanisms via Potassium Channels.

Basic & clinical pharmacology & toxicology
Cardiac arrhythmia is a common life-threatening cardiovascular disorder. Potassium channels play a crucial role in cardiac electrophysiology, and their dysfunction is closely associated with the occurrence and development of arrhythmia. Traditional C...

QTNet: Deep Learning for Estimating QT Intervals Using a Single Lead ECG.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
QT prolongation often leads to fatal arrhythmia and sudden cardiac death. Antiarrhythmic drugs can increase the risk of QT prolongation and therefore require strict post-administration monitoring and dosage control. Measurement of the QT interval fro...