AIMC Topic: Area Under Curve

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An interpretable machine learning-assisted diagnostic model for Kawasaki disease in children.

Scientific reports
Kawasaki disease (KD) is a syndrome of acute systemic vasculitis commonly observed in children. Due to its unclear pathogenesis and the lack of specific diagnostic markers, it is prone to being confused with other diseases that exhibit similar sympto...

An interpretable machine learning approach for detecting psoriatic arthritis in a UK primary care psoriasis cohort using electronic health records from the Clinical Practice Research Datalink.

Annals of the rheumatic diseases
OBJECTIVES: Develop an interpretable machine learning model to detect patients with newly diagnosed psoriatic arthritis (PsA) in a cohort of psoriasis patients and identify important clinical indicators of PsA in primary care.

Predicting outcomes of expectant and medical management in early pregnancy miscarriage using machine learning to develop and validate multivariable clinical prediction models.

BMC pregnancy and childbirth
OBJECTIVE: To determine whether readily available patient, ultrasound and treatment outcome data can be used to develop, validate and externally test two machine learning (ML) models for predicting the success of expectant and medical management of m...

Estimation of Ganciclovir Exposure in Adults Transplant Patients by Machine Learning.

The AAPS journal
INTRODUCTION: Valganciclovir, a prodrug of ganciclovir (GCV), is used to prevent cytomegalovirus infection after transplantation, with doses adjusted based on creatinine clearance (CrCL) to target GCV AUC0-24 h of 40-60 mg*h/L. This sometimes leads t...

Machine Learning-Based Mortality Prediction for Acute Gastrointestinal Bleeding Patients Admitted to Intensive Care Unit.

Current medical science
OBJECTIVE: The study aimed to develop machine learning (ML) models to predict the mortality of patients with acute gastrointestinal bleeding (AGIB) in the intensive care unit (ICU) and compared their prognostic performance with that of Acute Physiolo...

Development of a Machine Learning-Powered Optimized Lung Allocation System for Maximum Benefits in Lung Transplantation: A Korean National Data.

Journal of Korean medical science
BACKGROUND: An ideal lung allocation system should reduce waiting list deaths, improve transplant survival, and ensure equitable organ allocation. This study aimed to develop a novel lung allocation score (LAS) system, the MaxBenefit LAS, to maximize...

Development and validation of predictive models for diabetic retinopathy using machine learning.

PloS one
OBJECTIVE: This study aimed to develop and compare machine learning models for predicting diabetic retinopathy (DR) using clinical and biochemical data, specifically logistic regression, random forest, XGBoost, and neural networks.

New machine-learning models outperform conventional risk assessment tools in Gastrointestinal bleeding.

Scientific reports
Rapid and accurate identification of high-risk acute gastrointestinal bleeding (GIB) patients is essential. We developed two machine-learning (ML) models to calculate the risk of in-hospital mortality in patients admitted due to overt GIB. We analyze...

Development and validation of interpretable machine learning models for triage patients admitted to the intensive care unit.

PloS one
OBJECTIVES: Developing and validating interpretable machine learning (ML) models for predicting whether triaged patients need to be admitted to the intensive care unit (ICU).

Prediction of mortality risk in critically ill patients with systemic lupus erythematosus: a machine learning approach using the MIMIC-IV database.

Lupus science & medicine
OBJECTIVE: Early prediction of long-term outcomes in patients with systemic lupus erythematosus (SLE) remains a great challenge in clinical practice. Our study aims to develop and validate predictive models for the mortality risk.