AIMC Topic: Case-Control Studies

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Smartphone pupillometry with machine learning differentiates ischemic from hemorrhagic stroke: A pilot study.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVES: Similarities between acute ischemic and hemorrhagic stroke make diagnosis and triage challenging. We studied a smartphone-based quantitative pupillometer for differentiation of acute ischemic and hemorrhagic stroke.

Volumetric Breast Density Estimation From Three-Dimensional Reconstructed Digital Breast Tomosynthesis Images Using Deep Learning.

JCO clinical cancer informatics
PURPOSE: Breast density is a widely established independent breast cancer risk factor. With the increasing utilization of digital breast tomosynthesis (DBT) in breast cancer screening, there is an opportunity to estimate volumetric breast density (VB...

A novel approach to antimicrobial resistance: Machine learning predictions for carbapenem-resistant Klebsiella in intensive care units.

International journal of medical informatics
This study was conducted at Kocaeli University Hospital in Turkey and aimed to predict carbapenem-resistant Klebsiella pneumoniae infection in intensive care units using the Extreme Gradient Boosting (XGBoost) algorithm, a form of artificial intellig...

Predictive efficacy of machine-learning algorithms on intrahepatic cholestasis of pregnancy based on clinical and laboratory indicators.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
OBJECTIVES: Intrahepatic cholestasis of pregnancy (ICP), a condition exclusive to pregnancy, necessitates prompt identification and intervention to improve the perinatal outcomes. This study aims to develop suitable machine-learning models for predic...

Explainable machine learning identifies a polygenic risk score as a key predictor of pancreatic cancer risk in the UK Biobank.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: Predicting the risk of developing pancreatic ductal adenocarcinoma (PDAC) is of paramount importance, given its high mortality rate. Current PDAC risk prediction models rely on a limited number of variables, do not include genetics, and h...

Development of machine learning-based models to predict congenital heart disease: A matched case-control study.

International journal of medical informatics
BACKGROUND: The current congenital heart disease (CHD) prediction tools lack adequate interpretability and convenience, hindering the development of personalized CHD management strategies. We developed a machine learning-based risk stratification mod...

Machine learning approaches and genetic determinants that influence the development of type 2 diabetes mellitus: a genetic association study in Brazilian patients.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
This genetic association study including 120 patients with type 2 diabetes mellitus (T2DM) and 166 non-diabetic individuals aimed to investigate the association of polymorphisms in the genes GSTM1 and GSTT1 (gene deletion), GSTP1 (rs1695), ACE (rs464...

Integrating Metabolomics Domain Knowledge with Explainable Machine Learning in Atherosclerotic Cardiovascular Disease Classification.

International journal of molecular sciences
Metabolomic data often present challenges due to high dimensionality, collinearity, and variability in metabolite concentrations. Machine learning (ML) application in metabolomic analyses is enabling the extraction of meaningful information from comp...