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Chronic Disease

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Machine learning identifies a 5-serum cytokine panel for the early detection of chronic atrophy gastritis patients.

Cancer biomarkers : section A of Disease markers
BACKGROUND: Chronic atrophy gastritis (CAG) is a high-risk pre-cancerous lesion for gastric cancer (GC). The early and accurate detection and discrimination of CAG from benign forms of gastritis (e.g. chronic superficial gastritis, CSG) is critical f...

Development and External Validation of a Motor Intention-Integrated Prediction Model for Upper Extremity Motor Recovery After Intention-Driven Robotic Hand Training for Chronic Stroke.

Archives of physical medicine and rehabilitation
OBJECTIVE: To derive and validate a prediction model for minimal clinically important differences (MCIDs) in upper extremity (UE) motor function after intention-driven robotic hand training using residual voluntary electromyography (EMG) signals from...

Long COVID diagnostic with differentiation from chronic lyme disease using machine learning and cytokine hubs.

Scientific reports
The absence of a long COVID (LC) or post-acute sequelae of COVID-19 (PASC) diagnostic has profound implications for research and potential therapeutics given the lack of specificity with symptom-based identification of LC and the overlap of symptoms ...

A Comprehensive Natural Language Processing Pipeline for the Chronic Lupus Disease.

Studies in health technology and informatics
Electronic Health Records (EHRs) contain a wealth of unstructured patient data, making it challenging for physicians to do informed decisions. In this paper, we introduce a Natural Language Processing (NLP) approach for the extraction of therapies, d...

A Conformal Prediction Approach to Enhance Predictive Accuracy and Confidence in Machine Learning Application in Chronic Diseases.

Studies in health technology and informatics
Heterogeneity in chronic malignancies raises an increasing interest for the integration and study of predictive models. This study presents a machine learning model approach to predict outcomes and improve their trustworthiness in multi-factorial dis...

Machine learning applications in preventive healthcare: A systematic literature review on predictive analytics of disease comorbidity from multiple perspectives.

Artificial intelligence in medicine
Artificial intelligence is constantly revolutionizing biomedical research and healthcare management. Disease comorbidity is a major threat to the quality of life for susceptible groups, especially middle-aged and elderly patients. The presence of mul...

Deep Learning Based Shear Wave Detection and Segmentation Tool for Use in Point-of-Care for Chronic Liver Disease Assessments.

Ultrasound in medicine & biology
OBJECTIVE: As metabolic dysfunction-associated steatotic liver disease (MASLD) becomes more prevalent worldwide, it is imperative to create more accurate technologies that make it easy to assess the liver in a point-of-care setting. The aim of this s...

Machine learning-based model for worsening heart failure risk in Chinese chronic heart failure patients.

ESC heart failure
AIMS: This study aims to develop and validate an optimal model for predicting worsening heart failure (WHF). Multiple machine learning (ML) algorithms were compared, and the results were interpreted using SHapley Additive exPlanations (SHAP). A clini...

The accuracy of deep learning models for diagnosing maxillary fungal ball rhinosinusitis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
PURPOSE: To assess the accuracy of deep learning models for the diagnosis of maxillary fungal ball rhinosinusitis (MFB) and to compare the accuracy, sensitivity, specificity, precision, and F1-score with a rhinologist.