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Clinical Protocols

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Advanced Data Analytics for Clinical Research Part II: Application to Cardiothoracic Surgery.

Innovations (Philadelphia, Pa.)
In the first part of this series, we introduced the tools of Big Data, including Not Only Standard Query Language data warehouse, natural language processing (NLP), optical character recognition (OCR), and Internet of Things (IoT). There are nuances ...

Advanced Data Analytics for Clinical Research Part I: What are the Tools?

Innovations (Philadelphia, Pa.)
The concept of Big Data is changing the way that clinical research can be performed. Cardiothoracic surgeons need to understand the dynamic digital transformation taking place in the healthcare industry. In the last decade, technological advances and...

Adherence and acceptability of a robot-assisted Pivotal Response Treatment protocol for children with autism spectrum disorder.

Scientific reports
The aim of this study is to present a robot-assisted therapy protocol for children with ASD based on the current state-of-the-art in both ASD intervention research and robotics research, and critically evaluate its adherence and acceptability based o...

Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI Extension.

BMJ (Clinical research ed.)
The CONSORT 2010 (Consolidated Standards of Reporting Trials) statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency when evaluating new interventions. More recently, t...

Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI Extension.

BMJ (Clinical research ed.)
The SPIRIT 2013 (The Standard Protocol Items: Recommendations for Interventional Trials) statement aims to improve the completeness of clinical trial protocol reporting, by providing evidence-based recommendations for the minimum set of items to be a...

Deep learning diagnostic and risk-stratification pattern detection for COVID-19 in digital lung auscultations: clinical protocol for a case-control and prospective cohort study.

BMC pulmonary medicine
BACKGROUND: Lung auscultation is fundamental to the clinical diagnosis of respiratory disease. However, auscultation is a subjective practice and interpretations vary widely between users. The digitization of auscultation acquisition and interpretati...

Development and Evaluation of an Automated Protocol Recommendation System for Chest CT Using Natural Language Processing With CLEVER Terminology Word Replacement.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes
To evaluate the clinical performance of a Protocol Recommendation System (PRS) automatic protocolling of chest CT imaging requests. 322 387 consecutive historical imaging requests for chest CT between 2017 and 2022 were extracted from a radiology i...

CPRS: a clinical protocol recommendation system based on LLMs.

International journal of medical informatics
BACKGROUND: As fundamental documents in clinical trials, clinical trial protocols are intended to ensure that trials are conducted according to the objectives set by researchers. The advent of large models with superior semantic performance compared ...

Analysis of eligibility criteria clusters based on large language models for clinical trial design.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: Clinical trials (CTs) are essential for improving patient care by evaluating new treatments' safety and efficacy. A key component in CT protocols is the study population defined by the eligibility criteria. This study aims to evaluate the...