Alzheimer's disease (AD) is a complex, progressive, and irreversible neurodegenerative disorder marked by cognitive decline and memory loss. Early diagnosis is the most effective strategy to slow the disease's progression. Mild Cognitive Impairment (...
Dementia affects over 55 million people globally, with early cognitive decline, such as Mild Cognitive Impairment (MCI), often preceding neurodegenerative diseases. This decline impairs memory, attention, and Theory of Mind (ToM). Early intervention ...
Biomedical physics & engineering express
Jan 22, 2025
Mild cognitive impairment (MCI) is a significant predictor of the early progression of Alzheimer's disease (AD) and can serve as an important indicator of disease progression. However, many existing methods focus mainly on the image when processing b...
BACKGROUND: Intracerebral amyloid β (Aβ) accumulation is considered the initial observable event in the pathological process of Alzheimer's disease (AD). Efficient screening for amyloid pathology is critical for identifying patients for early treatme...
Elderly patients undergoing maintenance hemodialysis (MHD) face a heightened risk of cognitive frailty (CF), which significantly compromises quality of life. Early identification of at-risk individuals and timely intervention are essential. Neverthel...
BACKGROUND: The prompt and accurate identification of mild cognitive impairment (MCI) is crucial for preventing its progression into more severe neurodegenerative diseases. However, current diagnostic solutions, such as biomarkers and cognitive scree...
Journal of X-ray science and technology
Jan 13, 2025
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder. There are no drugs and methods for the treatment of AD, but early intervention can delay the deterioration of the disease. Therefore, the early diagnosis of AD and mild cognitive i...
BACKGROUND AND AIM: Changes in cognitive function are commonly associated with aging in patients with cardiovascular diseases. The objective of this research was to construct and validate a nomogram-based predictive model for the identification of co...
PURPOSE: Magnetization prepared rapid gradient echo (MPRAGE) is a useful three-dimensional (3D) T1-weighted sequence, but is not a priority in routine brain examinations. We hypothesized that converting 3D MRI localizer (AutoAlign Head) images to MPR...
BACKGROUND: Depression and cognitive impairments are prevalent among older adults, with evidence suggesting potential links to obesity and lipid metabolism disturbances. This study investigates the relationships between the triglyceride-glucose (TyG)...
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