American journal of Alzheimer's disease and other dementias
39688112
Alterations in Heart Rate (HR) and Heart Rate Variability (HRV) reflect autonomic dysfunction associated with neurodegeneration making them biomarkers suitable for detecting Mild Cognitive Impairment (MCI). The study involves 297 urban Indian parti...
BACKGROUND: Alzheimer's Disease (AD) poses a major challenge as a neurodegenerative disorder, and early detection is critical for effective intervention. Magnetic resonance imaging (MRI) is a critical tool in AD research due to its availability and c...
BACKGROUND AND OBJECTIVE: Early identification of post-stroke cognitive impairment (PSCI) is an important challenge for clinicians. In this study, we aimed to build a machine learning-based prediction model for PSCI and uncover potential risk factors...
Diabetes Mellitus combined with Mild Cognitive Impairment (DM-MCI) is a high incidence disease among the elderly. Patients with DM-MCI have considerably higher risk of dementia, whose daily self-care and life management (i.e. self-management) have a ...
Alzheimer's disease (AD), the most common neurodegenerative disorder world-wide, presents sex-specific differences in its manifestation and progression, necessitating personalized diagnostic approaches. Current procedures are often costly and invasiv...
AIM: We aimed to identify the characteristics of patients with diabetes who can derive cognitive benefits from intensive blood pressure (BP) treatment using machine learning methods.
Proteome changes associated with APOE4 variant carriage that are independent of Alzheimer's disease (AD) pathology and diagnosis are unknown. This study investigated APOE4 proteome changes in people with AD, mild cognitive impairment, and no impairme...
BACKGROUND: To diagnose Alzheimer disease (AD), individuals are classified according to the severity of their cognitive impairment. There are currently no specific causes or conditions for this disease.
The disease amyloid plaques, neurofibrillary tangles, synaptic dysfunction, and neuronal death gradually accumulate throughout Alzheimer's disease (AD), resulting in cognitive decline and functional disability. The challenges of dataset quality, inte...
Alzheimer's dementia (AD) is a neurodegenerative disorder that affects the central nervous system, causing the cells to stop working or die. The quality of life for individuals with AD steadily declines over time. While current treatments can relieve...