Magnetic resonance imaging (MRI) has shown that patients with end-stage renal disease have decreased gray matter volume and density. However, the cortical area and thickness in patients on hemodialysis are uncertain, and the relationship between pati...
INTRODUCTION: Recent research has suggested that neuroinflammation may be important in the pathogenesis of neurodegenerative diseases. Free-water diffusion (FWD) has been proposed as a non-invasive neuroimaging-based biomarker for neuroinflammation.
BACKGROUND: As the global population ages, the economic burden of dementia continues to rise. Social isolation-which includes limited social interaction and feelings of loneliness-negatively affects cognitive function and is a significant risk factor...
BACKGROUND: The rising prevalence of dementia necessitates a scalable solution to cognitive screening. Paper-based cognitive screening examinations are well-validated but minimally scalable. If a digital cognitive screening examination could replicat...
AIM: The aim of this study was to develop and validate a deep learning-based automatic classification algorithm for the medial temporal lobe atrophy (MTA) score in patients with cognitive impairment.
Recent advancements in cognitive neuroscience and digital technology have significantly accelerated the adoption of digital therapeutics for cognitive impairment. This viewpoint explores the innovative applications of digital therapeutics in the asse...
Alzheimer's disease (AD) is a common type of dementia, with mild cognitive impairment (MCI) being a key precursor. Early MCI diagnosis is crucial for slowing AD progression, but distinguishing MCI from normal controls (NC) is challenging due to subtl...
Apathy is common in persons with dementias, especially those in long-term care facilities (LTCs). Few pharmacologic options exist; a major strategy is to foster engagement in social, physical, and cognitive activities, but requires extensive personne...
BACKGROUND: The high prevalence of cognitive impairment (CI) in Chronic kidney disease (CKD) patients impacts their quality of life and prognosis, yet risk prediction models for CI in this population remain underexplored.
Alzheimer's disease (AD) is a prevalent neurodegenerative disease that primarily affects the elderly population. The early detection of mild cognitive impairment (MCI) holds significant clinical importance for prompt intervention and treatment of AD....
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