AIMC Topic: Cohort Studies

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Antifibrinolytic Therapy in Surgery for Adolescent Idiopathic Scoliosis Does the Level 1 Evidence Translate to Practice?

Bulletin of the Hospital for Joint Disease (2013)
INTRODUCTION: Previous randomized controlled trials have demonstrated the efficacy of antifibrinolytic agents in the reduction of intraoperative blood loss in adolescent idiopathic scoliosis (AIS) surgery. Tranexamic acid (TXA) was found to be more e...

Advancing In-Hospital Clinical Deterioration Prediction Models.

American journal of critical care : an official publication, American Association of Critical-Care Nurses
BACKGROUND: Early warning systems lack robust evidence that they improve patients' outcomes, possibly because of their limitation of predicting binary rather than time-to-event outcomes.

MABAL: a Novel Deep-Learning Architecture for Machine-Assisted Bone Age Labeling.

Journal of digital imaging
Bone age assessment (BAA) is a commonly performed diagnostic study in pediatric radiology to assess skeletal maturity. The most commonly utilized method for assessment of BAA is the Greulich and Pyle method (Pediatr Radiol 46.9:1269-1274, 2016; Arch ...

Comparison of Shallow and Deep Learning Methods on Classifying the Regional Pattern of Diffuse Lung Disease.

Journal of digital imaging
This study aimed to compare shallow and deep learning of classifying the patterns of interstitial lung diseases (ILDs). Using high-resolution computed tomography images, two experienced radiologists marked 1200 regions of interest (ROIs), in which 60...

Understanding Clinical Mammographic Breast Density Assessment: a Deep Learning Perspective.

Journal of digital imaging
Mammographic breast density has been established as an independent risk marker for developing breast cancer. Breast density assessment is a routine clinical need in breast cancer screening and current standard is using the Breast Imaging and Reportin...

Predicting Corticosteroid-Free Biologic Remission with Vedolizumab in Crohn's Disease.

Inflammatory bowel diseases
BACKGROUND AND AIMS: Vedolizumab (VDZ) is effective for Crohn's disease (CD) but costly and is slow to produce remission. Early knowledge of whether vedolizumab is likely to succeed is valuable for physicians, patients, and insurers.

Using Clinical Notes and Natural Language Processing for Automated HIV Risk Assessment.

Journal of acquired immune deficiency syndromes (1999)
OBJECTIVE: Universal HIV screening programs are costly, labor intensive, and often fail to identify high-risk individuals. Automated risk assessment methods that leverage longitudinal electronic health records (EHRs) could catalyze targeted screening...

Research: Use of Dry Electroencephalogram and Support Vector for Objective Pain Assessment.

Biomedical instrumentation & technology
The reliability of normal gel-based electrode electroencephalogram (EEG) for measuring pain has been validated. To date, however, few documented trials have used dry EEG for pain quantification. The primary goal of this study was to objectively quant...

Validation of Neutrophil CD64 Blood Biomarkers to Detect Mucosal Inflammation in Pediatric Crohn's Disease.

Inflammatory bowel diseases
BACKGROUND: In a pilot study, neutrophil CD64 surface expression was significantly elevated in newly diagnosed, pediatric-onset Crohn's disease. We aimed to test the CD64 biomarkers (neutrophil CD64 surface expression and soluble CD64) as determinate...