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Comorbidity

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Navigating the Intersection of Technology and Depression Precision Medicine.

Advances in experimental medicine and biology
This chapter primarily focuses on the progress in depression precision medicine with specific emphasis on the integrative approaches that include artificial intelligence and other data, tools, and technologies. After the description of the concept of...

Machine learning applications in preventive healthcare: A systematic literature review on predictive analytics of disease comorbidity from multiple perspectives.

Artificial intelligence in medicine
Artificial intelligence is constantly revolutionizing biomedical research and healthcare management. Disease comorbidity is a major threat to the quality of life for susceptible groups, especially middle-aged and elderly patients. The presence of mul...

Definition and Validation of Prognostic Phenotypes in Moderate Aortic Stenosis.

JACC. Cardiovascular imaging
BACKGROUND: Adverse outcomes from moderate aortic stenosis (AS) may be caused by progression to severe AS or by the effects of comorbidities. In the absence of randomized trial evidence favoring aortic valve replacement (AVR) in patients with moderat...

Comorbidity-based framework for Alzheimer's disease classification using graph neural networks.

Scientific reports
Alzheimer's disease (AD), the most prevalent form of dementia, requires early prediction for timely intervention. Current deep learning approaches, particularly those using traditional neural networks, face challenges such as handling high-dimensiona...

ML-Based Framework to Predict the Severity of the Symptomatology in Patients with Post-Acute COVID-19 Syndrome.

Studies in health technology and informatics
The paper describes a cohort of patients with post-acute COVID-19 syndrome, evaluated for the first time between week 3 and week 12 from the onset of symptoms following the acute COVID-19 infection. The patient's baseline clinical features were used ...

DAPNet: multi-view graph contrastive network incorporating disease clinical and molecular associations for disease progression prediction.

BMC medical informatics and decision making
BACKGROUND: Timely and accurate prediction of disease progress is crucial for facilitating early intervention and treatment for various chronic diseases. However, due to the complicated and longitudinal nature of disease progression, the capacity and...

A machine learning approach to stratify patients with hypermobile Ehlers-Danlos syndrome/hypermobility spectrum disorders according to disorders of gut brain interaction, comorbidities and quality of life.

Neurogastroenterology and motility
BACKGROUND: A high prevalence of disorders of gut-brain interaction (DGBI) exist in patients with hypermobile Ehlers-Danlos Syndrome (hEDS) and hypermobility spectrum disorders (HSD). However, it is unknown if clusters of hEDS/HSD patients exist whic...

An Approach for Combining Clinical Judgment with Machine Learning to Inform Medical Decision Making: Analysis of Nonemergency Surgery Strategies for Acute Appendicitis in Patients with Multiple Long-Term Conditions.

Medical decision making : an international journal of the Society for Medical Decision Making
BACKGROUND: Machine learning (ML) methods can identify complex patterns of treatment effect heterogeneity. However, before ML can help to personalize decision making, transparent approaches must be developed that draw on clinical judgment. We develop...

Machine learning and SHAP value interpretation for predicting comorbidity of cardiovascular disease and cancer with dietary antioxidants.

Redox biology
OBJECTIVE: To develop and validate a machine learning model incorporating dietary antioxidants to predict cardiovascular disease (CVD)-cancer comorbidity and to elucidate the role of antioxidants in disease prediction.

The Efficacy of a Food Supplement in the Treatment of Tinnitus with Comorbid Headache: A Statistical and Machine Learning Analysis with a Literature Review.

Audiology & neuro-otology
INTRODUCTION: Tinnitus, the perception of sound without an external auditory stimulus, affects approximately 10-15% of the population and is often associated with significant comorbidities such as headaches. These conditions can severely impact the q...