AIMC Topic: Computational Biology

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Deep learning methods for 3D structural proteome and interactome modeling.

Current opinion in structural biology
Bolstered by recent methodological and hardware advances, deep learning has increasingly been applied to biological problems and structural proteomics. Such approaches have achieved remarkable improvements over traditional machine learning methods in...

Artificial Intelligence Technology-Based Medical Information Processing and Emergency First Aid Nursing Management.

Computational and mathematical methods in medicine
This study was aimed at exploring the new management mode of medical information processing and emergency first aid nursing management under the new artificial intelligence technology. This study will use the artificial intelligence algorithm to opti...

Machine Learning-Based Automated Diagnostic Systems Developed for Heart Failure Prediction Using Different Types of Data Modalities: A Systematic Review and Future Directions.

Computational and mathematical methods in medicine
One of the leading causes of deaths around the globe is heart disease. Heart is an organ that is responsible for the supply of blood to each part of the body. Coronary artery disease (CAD) and chronic heart failure (CHF) often lead to heart attack. T...

GuiltyTargets: Prioritization of Novel Therapeutic Targets With Network Representation Learning.

IEEE/ACM transactions on computational biology and bioinformatics
The majority of clinical trials fail due to low efficacy of investigated drugs, often resulting from a poor choice of target protein. Existing computational approaches aim to support target selection either via genetic evidence or by putting potentia...

PDGNet: Predicting Disease Genes Using a Deep Neural Network With Multi-View Features.

IEEE/ACM transactions on computational biology and bioinformatics
The knowledge of phenotype-genotype associations is crucial for the understanding of disease mechanisms. Numerous studies have focused on developing efficient and accurate computing approaches to predict disease genes. However, owing to the sparsenes...

Account of Deep Learning-Based Ultrasonic Image Feature in the Diagnosis of Severe Sepsis Complicated with Acute Kidney Injury.

Computational and mathematical methods in medicine
This study was aimed at analyzing the diagnostic value of convolutional neural network models on account of deep learning for severe sepsis complicated with acute kidney injury and providing an effective theoretical reference for the clinical use of ...

Interpretable Model Based on Pyramid Scene Parsing Features for Brain Tumor MRI Image Segmentation.

Computational and mathematical methods in medicine
Due to the black box model nature of convolutional neural networks, computer-aided diagnosis methods based on depth learning are usually poorly interpretable. Therefore, the diagnosis results obtained by these unexplained methods are difficult to gai...

Nurturing diversity and inclusion in AI in Biomedicine through a virtual summer program for high school students.

PLoS computational biology
Artificial Intelligence (AI) has the power to improve our lives through a wide variety of applications, many of which fall into the healthcare space; however, a lack of diversity is contributing to limitations in how broadly AI can help people. The U...

Electrocardiogram Signal Classification in the Diagnosis of Heart Disease Based on RBF Neural Network.

Computational and mathematical methods in medicine
Heart disease is a common disease affecting human health. Electrocardiogram (ECG) classification is the most effective and direct method to detect heart disease, which is helpful to the diagnosis of most heart disease symptoms. At present, most ECG d...