AIMC Topic: Depressive Disorder, Major

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Identifying suicide attempts, ideation, and non-ideation in major depressive disorder from structural MRI data using deep learning.

Asian journal of psychiatry
The present study aims to identify suicide risks in major depressive disorders (MDD) patients from structural MRI (sMRI) data using deep learning. In this paper, we collected the sMRI data of 288 MDD patients, including 110 patients with suicide idea...

A Model of Normality Inspired Deep Learning Framework for Depression Relapse Prediction Using Audiovisual Data.

Computer methods and programs in biomedicine
BACKGROUND: Depression (Major Depressive Disorder) is one of the most common mental illnesses. According to the World Health Organization, more than 300 million people in the world are affected. A first depressive episode can be solved by a spontaneo...

Sex differences in rTMS treatment response: A deep learning-based EEG investigation.

Brain and behavior
INTRODUCTION: The present study aimed to investigate sex differences in response to repetitive transcranial magnetic stimulation (rTMS) in Major Depressive Disorder (MDD) patients. Identifying the factors that mediate treatment response to rTMS in MD...

Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression.

Science advances
Currently, psychiatric diagnoses are, in contrast to most other medical fields, based on subjective symptoms and observable signs and call for new and improved diagnostics to provide the most optimal care. On the basis of a deep learning approach, we...

Employing biochemical biomarkers for building decision tree models to predict bipolar disorder from major depressive disorder.

Journal of affective disorders
BACKGROUND: Conventional biochemical parameters may have predictive values for use in clinical identification between bipolar disorder (BD) and major depressive disorder (MDD).

Treatment selection using prototyping in latent-space with application to depression treatment.

PloS one
Machine-assisted treatment selection commonly follows one of two paradigms: a fully personalized paradigm which ignores any possible clustering of patients; or a sub-grouping paradigm which ignores personal differences within the identified groups. W...

Machine learning in the prediction of depression treatment outcomes: a systematic review and meta-analysis.

Psychological medicine
BACKGROUND: Multiple treatments are effective for major depressive disorder (MDD), but the outcomes of each treatment vary broadly among individuals. Accurate prediction of outcomes is needed to help select a treatment that is likely to work for a gi...

Accounting for symptom heterogeneity can improve neuroimaging models of antidepressant response after electroconvulsive therapy.

Human brain mapping
Depression symptom heterogeneity limits the identifiability of treatment-response biomarkers. Whether improvement along dimensions of depressive symptoms relates to separable neural networks remains poorly understood. We build on work describing thre...

Reproducibility of automated habenula segmentation via deep learning in major depressive disorder and normal controls with 7 Tesla MRI.

Scientific reports
The habenula is one of the most important brain regions for investigating the etiology of psychiatric diseases such as major depressive disorder (MDD). However, the habenula is challenging to delineate with the naked human eye in brain imaging due to...

Replication of machine learning methods to predict treatment outcome with antidepressant medications in patients with major depressive disorder from STAR*D and CAN-BIND-1.

PloS one
OBJECTIVES: Antidepressants are first-line treatments for major depressive disorder (MDD), but 40-60% of patients will not respond, hence, predicting response would be a major clinical advance. Machine learning algorithms hold promise to predict trea...