AIMC Topic: Diabetes Mellitus, Type 2
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MetaPheno: A critical evaluation of deep learning and machine learning in metagenome-based disease prediction.
Methods (San Diego, Calif.)
Mar 16, 2019
The human microbiome plays a number of critical roles, impacting almost every aspect of human health and well-being. Conditions in the microbiome have been linked to a number of significant diseases. Additionally, revolutions in sequencing technology...
Discovering the Type 2 Diabetes in Electronic Health Records Using the Sparse Balanced Support Vector Machine.
IEEE journal of biomedical and health informatics
Feb 13, 2019
The diagnosis of type 2 diabetes (T2D) at an early stage has a key role for an adequate T2D integrated management system and patient's follow-up. Recent years have witnessed an increasing amount of available electronic health record (EHR) data and ma...
Circulating Levels of Soluble Klotho and Fibroblast Growth Factor 23 in Diabetic Patients and Its Association with Early Nephropathy.
Archives of medical research
Feb 1, 2019
INTRODUCTION: Diabetic nephropathy is a leading cause of chronic kidney disease (CKD). In diabetes, changes in serum levels of both soluble alpha Klotho (sKL) and fibroblast growth factor 23 (FGF-23) have been associated with CKD progression.
Quantitation of serum 25(OH)D2 and 25(OH)D3 concentrations by liquid chromatography tandem mass spectrometry in patients with diabetes mellitus.
Journal of food and drug analysis
Dec 31, 2018
Vitamin D has been considered to regulate calcium and phosphorus homeostasis and to preserve skeletal integrity. Serum 25-hydroxyvitamin D (25(OH)D) is the best indicator of vitamin D levels. The association of serum 25(OH)D deficiency with increased...
Picomolar detection of retinol binding protein 4 for early management of type II diabetes.
Biosensors & bioelectronics
Dec 24, 2018
Type (II) diabetes is one of the major threats to mankind as it causes insulin resistance in human body and Retinol Binding Protein 4 (RBP4) is currently considered as a potential biomarker for early management of this disease. Hence a low-level dete...
Fibroblast growth factor 21 association with subclinical atherosclerosis and arterial stiffness in type 2 diabetes.
Diabetes & metabolic syndrome
Dec 19, 2018
AIM: To evaluate the association of serum FGF21 with subclinical atherosclerosis and pulse wave velocity, a marker of arterial stiffness, in type 2 diabetes Egyptian patients.
Insulin resistance and adrenal incidentalomas: A bidirectional relationship.
Maturitas
Dec 5, 2018
An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological modality, independent of an endocrinological investigation. In this review, we aimed to investigate the possible reasons behind the increased frequency in AI detec...
Selecting Test Cases from the Electronic Health Record for Software Testing of Knowledge-Based Clinical Decision Support Systems.
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Software testing of knowledge-based clinical decision support systems is challenging, labor intensive, and expensive; yet, testing is necessary since clinical applications have heightened consequences. Thoughtful test case selection improves testing ...
Scalable Electronic Phenotyping For Studying Patient Comorbidities.
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Over 75 million Americans have multiple concurrent chronic conditions and medical decision making for these patients is mostly based on retrospective cohort studies. Current methods to generate cohorts of patients with comorbidities are neither scala...
Phenotyping through Semi-Supervised Tensor Factorization (PSST).
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
A computational phenotype is a set of clinically relevant and interesting characteristics that describe patients with a given condition. Various machine learning methods have been proposed to derive phenotypes in an automatic, high-throughput manner....
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