AIMC Topic: Disease Progression
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Explainable machine learning on clinical features to predict and differentiate Alzheimer's progression by sex: Toward a clinician-tailored web interface.
Journal of the neurological sciences
Dec 19, 2024
Alzheimer's disease (AD), the most common neurodegenerative disorder world-wide, presents sex-specific differences in its manifestation and progression, necessitating personalized diagnostic approaches. Current procedures are often costly and invasiv...
Machine learning models predict the progression of long-term renal insufficiency in patients with renal cancer after radical nephrectomy.
BMC nephrology
Dec 18, 2024
BACKGROUND: Chronic Kidney Disease (CKD) is a common severe complication after radical nephrectomy in patients with renal cancer. The timely and accurate prediction of the long-term progression of renal function post-surgery is crucial for early inte...
Machine learning-based selection of immune cell markers in osteosarcoma: prognostic determination and validation of CLK1 in disease progression.
Frontiers in immunology
Dec 17, 2024
INTRODUCTION: Osteosarcoma (OS) is a malignancy of the bone that mainly afflicts younger individuals. Despite existing treatment approaches, patients with metastatic or recurrent disease generally face poor prognoses. A greater understanding of the t...
Disease Progression
DNA Copy Number Variations
Female
Humans
Cell Line, Tumor
Protein Serine-Threonine Kinases
Lymphocytes, Tumor-Infiltrating
Tumor Microenvironment
Machine Learning
Gene Expression Regulation, Neoplastic
Osteosarcoma
Biomarkers, Tumor
Prognosis
Cell Proliferation
Bone Neoplasms
Male
Protein-Tyrosine Kinases
L-MAE: Longitudinal masked auto-encoder with time and severity-aware encoding for diabetic retinopathy progression prediction.
Computers in biology and medicine
Dec 16, 2024
Pre-training strategies based on self-supervised learning (SSL) have demonstrated success as pretext tasks for downstream tasks in computer vision. However, while SSL methods are often domain-agnostic, their direct application to medical imaging is c...
Random survival forest model for early prediction of Alzheimer's disease conversion in early and late Mild cognitive impairment stages.
PloS one
Dec 13, 2024
With a clinical trial failure rate of 99.6% for Alzheimer's Disease (AD), early diagnosis is critical. Machine learning (ML) models have shown promising results in early AD prediction, with survival ML models outperforming typical classifiers by prov...
Artificial intelligence in predicting chronic kidney disease prognosis. A systematic review and meta-analysis.
Renal failure
Dec 11, 2024
BACKGROUND: Chronic kidney disease (CKD) is a common condition that can lead to serious health complications. Artificial Intelligence (AI) has shown the potential to improve the prediction of CKD progression, offering increased accuracy over traditio...
Digital Pathology-based Artificial Intelligence Biomarker Validation in Metastatic Prostate Cancer.
European urology oncology
Dec 10, 2024
BACKGROUND AND OBJECTIVE: Owing to the expansion of treatment options for metastatic hormone-sensitive prostate cancer (mHSPC) and an appreciation of clinical subgroups with differential prognosis and treatment responses, prognostic and predictive bi...
MicroRNA signature for early prediction of knee osteoarthritis structural progression using integrated machine and deep learning approaches.
Osteoarthritis and cartilage
Nov 29, 2024
OBJECTIVE: Conventional methodologies are ineffective in predicting the rapid progression of knee osteoarthritis (OA). MicroRNAs (miRNAs) show promise as biomarkers for patient stratification. We aimed to develop a miRNA prognosis model for identifyi...
Thickness Speed Progression Index: Machine Learning Approach for Keratoconus Detection.
American journal of ophthalmology
Nov 27, 2024
PURPOSE: To develop and validate a pachymetry-based machine learning (ML) index for differentiating keratoconus, keratoconus suspect, and normal corneas.
Effective Alzheimer's disease detection using enhanced Xception blending with snapshot ensemble.
Scientific reports
Nov 26, 2024
Alzheimer's disease (AD), a prevalent neurodegenerative disorder, leads to progressive dementia, which impairs decision-making, problem-solving, and communication. While there is no cure, early detection can facilitate treatments to slow its progress...
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