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Disease Progression

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AI driven analysis of MRI to measure health and disease progression in FSHD.

Scientific reports
Facioscapulohumeral muscular dystrophy (FSHD) affects roughly 1 in 7500 individuals. While at the population level there is a general pattern of affected muscles, there is substantial heterogeneity in muscle expression across- and within-patients. Th...

Predicting Alzheimer's Disease Progression Using a Versatile Sequence-Length-Adaptive Encoder-Decoder LSTM Architecture.

IEEE journal of biomedical and health informatics
Detecting Alzheimer's disease (AD) accurately at an early stage is critical for planning and implementing disease-modifying treatments that can help prevent the progression to severe stages of the disease. In the existing literature, diagnostic test ...

Enhanced choroid plexus segmentation with 3D UX-Net and its association with disease progression in multiple sclerosis.

Multiple sclerosis and related disorders
BACKGROUND: The choroid plexus (CP) is suggested to be closely associated with the neuroinflammation of multiple sclerosis (MS). Segmentation based on deep learning (DL) could facilitate rapid and reproducible volume assessment of the CP, which is cr...

Predicting changes in brain metabolism and progression from mild cognitive impairment to dementia using multitask Deep Learning models and explainable AI.

NeuroImage
BACKGROUND: The prediction of Alzheimer's disease (AD) progression from its early stages is a research priority. In this context, the use of Artificial Intelligence (AI) in AD has experienced a notable surge in recent years. However, existing investi...

Characterizing Disease Progression in Parkinson's Disease from Videos of the Finger Tapping Test.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
INTRODUCTION: Parkinson's disease (PD) is characterized by motor symptoms whose progression is typically assessed using clinical scales, namely the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS). Despite its reliabilit...

Prediction of Alzheimer's disease progression within 6 years using speech: A novel approach leveraging language models.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Identification of individuals with mild cognitive impairment (MCI) who are at risk of developing Alzheimer's disease (AD) is crucial for early intervention and selection of clinical trials.

Group-informed attentive framework for enhanced diabetes mellitus progression prediction.

Frontiers in endocrinology
The increasing prevalence of Diabetes Mellitus (DM) as a global health concern highlights the paramount importance of accurately predicting its progression. This necessity has propelled the use of deep learning's advanced analytical and predictive ca...

Evaluation of machine learning-based classification of clinical impairment and prediction of clinical worsening in multiple sclerosis.

Journal of neurology
BACKGROUND: Robust predictive models of clinical impairment and worsening in multiple sclerosis (MS) are needed to identify patients at risk and optimize treatment strategies.

Prediction of short-term progression of COVID-19 pneumonia based on chest CT artificial intelligence: during the Omicron epidemic.

BMC infectious diseases
BACKGROUND AND PURPOSE: The persistent progression of pneumonia is a critical determinant of adverse outcomes in patients afflicted with COVID-19. This study aimed to predict personalized COVID-19 pneumonia progression between the duration of two wee...