AIMC Topic: Feces

Clear Filters Showing 91 to 100 of 117 articles

Organism burden, toxin concentration, and lactoferrin concentration do not distinguish between clinically significant and nonsignificant diarrhea in patients with Clostridium difficile.

Diagnostic microbiology and infectious disease
Clostridium difficile infection is often overdiagnosed in patients with mild diarrhea. We evaluated 4 biomarkers as surrogates for clinically significant diarrhea (≥ 3 episodes in 24 hours) in 59 PCR-positive patients with and 59 PCR-positive patient...

Automatic Identification of Human Erythrocytes in Microscopic Fecal Specimens.

Journal of medical systems
Traditional fecal erythrocyte detection is performed via a manual operation that is unsuitable because it depends significantly on the expertise of individual inspectors. To recognize human erythrocytes automatically and precisely, automatic segmenta...

Predicting fecal sources in waters with diverse pollution loads using general and molecular host-specific indicators and applying machine learning methods.

Journal of environmental management
In this study we use a machine learning software (Ichnaea) to generate predictive models for water samples with different concentrations of fecal contamination (point source, moderate and low). We applied several MST methods (host-specific Bacteroide...

Absolute oral bioavailability and pharmacokinetics of canagliflozin: A microdose study in healthy participants.

Clinical pharmacology in drug development
Absolute oral bioavailability of canagliflozin was assessed by simultaneous oral administration with intravenous [(14) C]-canagliflozin microdose infusion in nine healthy men. Pharmacokinetics of canagliflozin, [(14) C]-canagliflozin, and total radio...

Novel robotic tools used for the detection of faecal shedding of Escherichia coli resistant to critically important antimicrobials in healthy dogs.

Veterinary microbiology
Escherichia coli recovered from dogs with clinical conditions such as urinary tract infections are often used to assess populations for resistance to critically important antimicrobials (CIAs). Despite the potential importance of such strains, the nu...

Four Different Artificial Intelligence Models Logistic Regression to Enhance the Diagnostic Accuracy of Fecal Immunochemical Test in the Detection of Colorectal Carcinoma in a Screening Setting.

Anticancer research
BACKGROUND/AIM: This study aimed to evaluate the diagnostic accuracy (DA) of four artificial intelligence (AI) models compared to logistic regression (LR) in enhancing the performance of the fecal immunochemical test (FIT) for the detection of colore...

Development and validation of the Open-Source Automatic Bowel Preparation Scale.

Gastrointestinal endoscopy
BACKGROUND AND AIMS: Insufficient bowel preparation accounts for up to 42% of missed adenomas in colonoscopy. However, major analysis programs found no correlation between adenoma detection rate and the human-rated Boston Bowel Preparation Scale (BBP...

An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study.

Science translational medicine
There are currently no licensed vaccines for norovirus, a leading cause of epidemic and endemic gastroenteritis worldwide. Clinical advancement of promising vaccine candidates from phase 2 studies to phase 3 field trials has been hampered by the lack...

Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study.

Genome medicine
BACKGROUND: The microbiome of adolescents is poorly understood, as are factors influencing its composition. We aimed to describe the healthy adolescent microbiome and identify early-life and concurrent predictors of its composition.