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From laser-on time to lithotripsy duration: improving the prediction of lithotripsy duration with 'Kidney Stone Calculator' using artificial intelligence.
World journal of urology
Jun 26, 2025
INTRODUCTION: "Kidney Stone Calculator" (KSC) helps to plan flexible ureteroscopy, providing the stone volume (SV) and an estimated duration of laser lithotripsy (eLD). eLD is calculated from in vitro ablation rates and SV. KSC's accuracy has been de...
Epicardial adipose tissue, myocardial remodelling and adverse outcomes in asymptomatic aortic stenosis: a post hoc analysis of a randomised controlled trial.
Heart (British Cardiac Society)
Jun 26, 2025
BACKGROUND: Epicardial adipose tissue represents a metabolically active visceral fat depot that is in direct contact with the left ventricular myocardium. While it is associated with coronary artery disease, little is known regarding its role in aort...
Comparative investigation of bagging enhanced machine learning for early detection of HCV infections using class imbalance technique with feature selection.
PloS one
Jun 26, 2025
Around 1.5 million new cases of Hepatitis C Virus (HCV) are diagnosed globally each year (World Health Organization, 2023). Consequently, there is a pressing need for early diagnostic methods for HCV. This study investigates the prognostic accuracy o...
Effect of the exposure to brominated flame retardants on hyperuricemia using interpretable machine learning algorithms based on the SHAP methodology.
PloS one
Jun 26, 2025
BACKGROUND: Brominated flame retardants (BFRs) are classified as important endocrine disruptors and persistent organic pollutants; nevertheless, there is no comprehensive investigation to evaluate the association between BFRs and hyperuricemia, and t...
Evaluating real-world performance of an automated offline glaucoma AI on a smartphone fundus camera across glaucoma severity stages.
PloS one
Jun 26, 2025
PURPOSE: Leveraging an artificial intelligence system (AI) for glaucoma screening can mitigate the current challenges and provide prompt detection and management crucial in averting irreversible blindness. The study reports the real-world performance...
Multi-site validation of an interpretable model to analyze breast masses.
PloS one
Jun 26, 2025
An external validation of IAIA-BL-a deep-learning based, inherently interpretable breast lesion malignancy prediction model-was performed on two patient populations: 207 women ages 31 to 96, (425 mammograms) from iCAD, and 58 women (104 mammograms) f...
Progression and natural history of Atypical Parkinsonism (ATPARK): Protocol for a longitudinal follow-up study from an underrepresented population.
PloS one
Jun 26, 2025
BACKGROUND: Atypical Parkinsonian Syndromes (APS) form the third largest group of neurodegenerative disorders including Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA), and Corticobasal Syndrome (CBS). These conditions are charact...
Exploring the relationship between graft dysfunction with serum metabolites and inflammatory proteins: integrating Mendelian randomization, single-cell analysis, machine learning, and SHAP methods for comprehensive analysis.
Renal failure
Jun 25, 2025
BACKGROUND: The exact mechanism of graft dysfunction has not been fully clarified. We aimed to explore the causal effects of serum metabolites on graft dysfunction and the mediating role of inflammatory proteins.
Multi-parameter MRI deep learning model for lymphovascular invasion assessment in invasive breast ductal carcinoma: A multicenter, retrospective study.
Clinical radiology
Jun 25, 2025
AIMS: To investigate the value of multi-parametric magnetic resonance imaging (MRI)-based deep learning (DL) in predicting the Lymphovascular Invasion (LVI) status of invasive breast ductal cancer (IBDC).
Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.
Clinical nutrition (Edinburgh, Scotland)
Jun 25, 2025
BACKGROUND & AIMS: Studies in-vitro and in animals propose that vitamins and minerals can alter the human gut microbiome. Human trials replicating these findings are scarce or used micronutrient supplementation in supraphysiological doses. We explore...
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