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The Gut Microbiota in Young Adults with High-Functioning Autism Spectrum Disorder and Its Performance as Diagnostic Biomarkers.
Nutrients
May 22, 2025
Diagnosing ASD in adults presents unique challenges, and there are currently no specific biomarkers for this condition. Most existing studies on the gut microbiota in ASD are conducted in children; however, the composition of the gut microbiota in c...
Assessing ChatGPT adoption in Jordanian medical education: a UTAUT model approach.
BMC medical education
May 22, 2025
BACKGROUND: ChatGPT has shown significant promise in transforming medical education by streamlining research and improving teaching methods. However, its adoption in Middle Eastern medical education has remained underexplored. This study investigated...
Association of sarcopenia with all-cause and cause-specific mortality in cancer patients: development and validation of a 3-year and 5-year survival prediction model.
BMC cancer
May 22, 2025
BACKGROUND: Sarcopenia is a clinicopathological condition characterized by a decrease in muscle strength and muscle mass, playing a crucial role in the prognosis of cancer. Therefore, this study aims to investigate the association between sarcopenia ...
The value of radiomics features of white matter hyperintensities in diagnosing cognitive frailty: a study based on T2-FLAIR imaging.
BMC medical imaging
May 22, 2025
BACKGROUND: White matter hyperintensities (WMHs) are closely associated with cognitive frailty (CF). This study aims to explore the potential diagnostic value of WMHs for CF based on radiomics approaches, thereby providing a novel methodology for the...
Using ML techniques to predict extubation outcomes for patients with central nervous system injuries in the Yun-Gui Plateau.
Scientific reports
May 22, 2025
No predictive models have been reported for tracheostomy extubation success in plateau region rehabilitation departments. Hence, the primary objective of this retrospective study was to evaluate the predictive capabilities of different models for ext...
Interpretable prediction of drug synergy for breast cancer by random forest with features from Boolean modeling of signaling pathways.
Scientific reports
May 22, 2025
Breast cancer is a complex and challenging disease to treat, and despite progress in combating it, drug resistance remains a significant hindrance. Drug combinations have shown promising results in improving therapeutic outcomes, and many machine lea...
Apnea detection using wrist actigraphy in patients with heterogeneous sleep disorders.
Scientific reports
May 22, 2025
Obstructive sleep apnea (OSA) and related hypoxia are well-established cardiovascular and neurocognitive risk factors. Current multi-sensor diagnostic approaches are intrusive and prone to misdiagnosis when simplified. This study introduces an enhanc...
Imputing single-cell protein abundance in multiplex tissue imaging.
Nature communications
May 22, 2025
Multiplex tissue imaging enables single-cell spatial proteomics and transcriptomics but remains limited by incomplete molecular profiling, tissue loss, and probe failure. Here, we apply machine learning to impute single-cell protein abundance using m...
Effectiveness and Methodologies of Virtual Reality Dental Simulators for Veneer Tooth Preparation Training: Randomized Controlled Trial.
Journal of medical Internet research
May 22, 2025
BACKGROUND: Virtual reality (VR) simulators are increasingly used in dental education, offering advantages such as repeatable practice and immediate feedback. However, evidence comparing their efficacy to traditional phantom heads for veneer preparat...
Artificial intelligence in primary care: a plausible prospect or distant delusion?
The British journal of general practice : the journal of the Royal College of General Practitioners
May 22, 2025
BACKGROUND: Artificial intelligence (AI) offers an innovative means of changing primary care, yet the impressions of primary care professionals (PCPs) on this potentially revolutionary resource remains unclear.
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