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Feasibility study of a general model for synthetic CT generation in MRI-guided extracranial radiotherapy.
Biomedical physics & engineering express
May 19, 2025
This study aims to investigate the feasibility of a single general model to synthesize CT images across body sites, thorax, abdomen, and pelvis, to support treatment planning for MRI-only radiotherapy. A total of 157 patients who received MRI-guided ...
Development and validation of a nomogram for differentiating immune checkpoint inhibitor-related pneumonitis from pneumonia in patients undergoing immunochemotherapy: a multicenter, real-world, retrospective study.
Frontiers in immunology
May 19, 2025
BACKGROUND: Immune Checkpoint Inhibitor-related Pneumonitis (CIP) exhibits high morbidity and mortality rates in the real world, often coexisting with pneumonia, particularly after immunochemotherapy. We aimed to develop and validate a non-invasive n...
Study on the relationship between vaginal dose and radiation-induced vaginal injury following cervical cancer radiotherapy, and model development.
Frontiers in public health
May 19, 2025
OBJECTIVE: This study investigates the relationship between vaginal radiation dose and radiation-induced vaginal injury in cervical cancer patients, with the aim of developing a risk prediction model to support personalized treatment strategies.
[Cluster predictors of trajectories of leisure-time physical activity intensity in men and women from ELSA-Brasil].
Cadernos de saude publica
May 19, 2025
The maintenance of physical activity over time is a challenge for public health. Predictors of different physical activity intensities have not been sufficiently analyzed. This study aimed to identify clusters of trajectories of physical activity int...
A data-driven scoring framework for personalized employee health check-ups: Integrating historical laboratory trends and evidence-based prevalence.
International journal of medical informatics
May 18, 2025
INTRODUCTION: Rising healthcare costs and growing demand for personalized preventive care have highlighted the need for data-driven approaches to optimize health check-ups, particularly in corporate settings. This study presents a scoring-based platf...
Global burden of vertebral fractures from 1990 to 2021 and projections for the next three decades.
Journal of orthopaedic surgery and research
May 17, 2025
BACKGROUND: Vertebral fractures are linked to significant disability and mortality risks. Yet, existing studies on their global burden are outdated and lack predictive foresight.
Exploring potential methylation markers for ovarian cancer from cervical scraping samples.
Human genomics
May 17, 2025
BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate drops from 92% with early-stage diagnosis compared to 31% with late-stage diagnosis. Current diagnos...
Brain metabolic imaging-based model identifies cognitive stability in prodromal Alzheimer's disease.
Scientific reports
May 17, 2025
The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) has created a pressing need for the ability to accurately identify optimal candidates for anti-amyloid therapy, specifically those with evidence for inc...
Construction and validation of a pain facial expressions dataset for critically ill children.
Scientific reports
May 17, 2025
Automatic pain assessment for non-communicative children is in high demand. However, the availability of related training datasets remains limited. This study focuses on creating a large-scale dataset of pain facial expressions specifically for Chine...
A Point Cloud Generation Network for Automatic Prediction of Postoperative Maxillofacial Soft Tissue.
Annals of biomedical engineering
May 16, 2025
PURPOSE: In the planning of maxillofacial surgery, accurately evaluating the postoperative soft tissue area is crucial. This allows doctors to provide patients with better morphological recovery while ensuring the restoration of normal functional are...
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