Diabetic kidney disease (DKD) progression is not well understood. Using high-throughput proteomics, biostatistical, pathway and machine learning tools, we examine the urinary Complement proteome in two prospective cohorts with type 1 or 2 diabetes an...
This study aimed to develop a reliable and explainable predictive model for illicit drug use (IDU). The model uses a machine learning (ML) algorithm to predict IDU using hematological differences between illicit drug users (IDUr) and non-users (n-IDU...
Squamous cell carcinoma (SCC) and high-grade dysplasia (HGD) are two different pathological entities; however, they sometimes share similarities in histological structure depending on the context. Thus, distinguishing between the two may require care...
This study investigated the effects of feature augmentation, which uses generated images with specific imaging features, on the performance of isocitrate dehydrogenase (IDH) mutation prediction models in gliomas. A total of 598 patients were included...
The mortality rates have been increasing for glioma in adolescents and young adults (AYAs, aged 15-39 years). However, current biomarkers for clinical assessment in AYAs glioma are limited, prompting the urgent need for identifying ideal prognostic s...
BACKGROUND: Given the high prevalence and cost of Alzheimer disease (AD), it is crucial to develop equitable interventions to address lifestyle factors associated with AD incidence (eg, depression). While lifestyle interventions show promise for redu...
BACKGROUND: The risk of developing atherosclerotic cardiovascular disease (ASCVD) varies among individuals and is related to a variety of lifestyle factors in addition to the presence of chronic diseases.
OBJECTIVE: We aimed to compare the Belun Sleep Platform (BSP), an artificial intelligence-driven home sleep testing device, with polysomnography (PSG) for diagnosing obstructive sleep apnea. The BSP analyzes oxygen saturation, heart rate, and acceler...
The amygdala plays a central role in emotion, memory, and decision-making and comprises approximately 13 distinct nuclei with connectivity. Despite its functional importance, high-resolution subnuclear mapping is challenging. This study aimed to cons...
Diabetic retinopathy (DR) is a microvascular complication of diabetes that can lead to blindness if left untreated. Regular monitoring is crucial for detecting early signs of referable DR, and the progression to moderate to severe non-proliferative D...
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