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Machine learning-based integration identifies plasma cells-related gene signature ST6GAL1 in idiopathic pulmonary fibrosis.

BMC pulmonary medicine
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a rare, progressive, and fibrotic disease with poor prognosis that lacks treatment options. As a major component of the lung adaptive immune system, plasma cells play a crucial regulatory role during...

Crisis-line workers' perspectives on AI in suicide prevention: a qualitative exploration of risk and opportunity.

BMC public health
BACKGROUND: Crisis support services offer crucial intervention for individuals in acute distress, providing timely access to trained volunteers whose human connection is key to the effectiveness of these services. However, there are significant dispa...

Enhanced machine learning models for predicting three-year mortality in Non-STEMI patients aged 75 and above.

BMC geriatrics
BACKGROUND: Non-ST segment elevation myocardial infarction (Non-STEMI) is a severe cardiovascular condition mainly affecting individuals aged 75 and above, who are at higher risk of mortality due to age-related vulnerabilities and other health issues...

Development of an electronic health record-based Human Immunodeficiency Virus (HIV) risk prediction model for women, incorporating social determinants of health.

BMC public health
BACKGROUND: Human Immunodeficiency Virus (HIV) pre-exposure prophylaxis (PrEP) prevents HIV transmission but has low uptake among women. Identifying women who could benefit from PrEP remains a challenge. This study developed a women-specific model to...

Methodological conduct and risk of bias in studies on prenatal birthweight prediction models using machine learning techniques: a systematic review.

BMC pregnancy and childbirth
OBJECTIVE: To assess the methodological quality and the risk of bias, of studies that developed prediction models using Machine Learning (ML) techniques to estimate prenatal birthweight.

Prediction of caesarean section birth using machine learning algorithms among pregnant women in a district hospital in Ghana.

BMC pregnancy and childbirth
BACKGROUND: Machine learning algorithms may contribute to improving maternal and child health, including determining the suitability of caesarean section (CS) births in low-resource countries. Despite machine learning algorithms offering a more robus...

Interpretable machine learning for depression recognition with spatiotemporal gait features among older adults: a cross-sectional study in Xiamen, China.

BMC geriatrics
OBJECTIVE: Depression in older adults is a growing public health concern, yet there is still a lack of convenient and real-time methods for depressive symptoms identification. This study aims to develop a gait-based depression recognition method for ...

Deep learning-based quantitative analysis of glomerular morphology in IgA nephropathy whole slide images and its prognostic implications.

Scientific reports
Kidney pathology of immunoglobulin A nephropathy (IgAN), which is the key finding of both diagnosis and risk stratification, involves labor-intensive manual interpretation as well as unavoidable interpreter-dependent variabilities. We propose artific...

Cohesive data analysis for the identification of prognostic hub genes and significant pathways associated with HER2 + and TN breast cancer types.

Scientific reports
Breast cancer is the most prevalent and lethal form of cancer being the utmost common medical concern of women. Breast cancer etiology implicates numerous cellular protein receptors such as estrogen receptors (ER), progesterone receptors (PR), and hu...

A novel XAI framework for explainable AI-ECG using generative counterfactual XAI (GCX).

Scientific reports
Generative Counterfactual Explainable Artificial Intelligence (XAI) offers a novel approach to understanding how AI models interpret electrocardiograms (ECGs). Traditional explanation methods focus on highlighting important ECG segments but often fai...