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Incorporation of explainable artificial intelligence in ensemble machine learning-driven pancreatic cancer diagnosis.

Scientific reports
Despite the strides made in medical science, pancreatic cancer continues to be a threat, highlighting the urgent need for creative strategies to address this concern. Recently, a potential approach that has attracted significant attention is using ma...

Development and validation of a machine learning risk prediction model for asthma attacks in adults in primary care.

NPJ primary care respiratory medicine
Primary care consultations provide an opportunity for patients and clinicians to assess asthma attack risk. Using a data-driven risk prediction tool with routinely collected health records may be an efficient way to aid promotion of effective self-ma...

Prediction of Reactivation After Antivascular Endothelial Growth Factor Monotherapy for Retinopathy of Prematurity: Multimodal Machine Learning Model Study.

Journal of medical Internet research
BACKGROUND: Retinopathy of prematurity (ROP) is the leading preventable cause of childhood blindness. A timely intravitreal injection of antivascular endothelial growth factor (anti-VEGF) is required to prevent retinal detachment with consequent visi...

Association of acute kidney injury with 1-year mortality in granulomatosis with polyangiitis patients: a cohort study using mediation analyses and machine learning.

Rheumatology international
To investigate the correlation between acute kidney injury (AKI) and 1-year mortality in patients with granulomatosis with polyangiitis (GPA). Clinical data for GPA patients were extracted from the MIMIC-IV (version 3.0) database. Logistic and Cox re...

Machine learning technique-based four-autoantibody test for early detection of esophageal squamous cell carcinoma: a multicenter, retrospective study with a nested case-control study.

BMC medicine
BACKGROUND: Autoantibodies represent promising diagnostic blood-based biomarkers that may be generated prior to the first clinically detectable signs of cancers. In present study, we aimed to identify a novel optimized autoantibody panel with high di...

Constructing a neural network model based on tumor-infiltrating lymphocytes (TILs) to predict the survival of hepatocellular carcinoma patients.

PeerJ
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver cancer worldwide, and early pathological diagnosis is crucial for formulating treatment plans. Despite the widespread attention to pathology in the treatment of HCC patients,...

An informed machine learning based environmental risk score for hypertension in European adults.

Artificial intelligence in medicine
BACKGROUND: The exposome framework seeks to unravel the cumulated effects of environmental exposures on health. However, existing methods struggle with challenges including multicollinearity, non-linearity and confounding. To address these limitation...

Cascade learning in multi-task encoder-decoder networks for concurrent bone segmentation and glenohumeral joint clinical assessment in shoulder CT scans.

Artificial intelligence in medicine
Osteoarthritis is a degenerative condition that affects bones and cartilage, often leading to structural changes, including osteophyte formation, bone density loss, and the narrowing of joint spaces. Over time, this process may disrupt the glenohumer...

Unraveling Parkinson's disease motor subtypes: A deep learning approach based on spatiotemporal dynamics of EEG microstates.

Neurobiology of disease
BACKGROUND: Despite prior studies on early-stage Parkinson's disease (PD) brain connectivity and temporal patterns, differences between tremor-dominant (TD) and postural instability/gait difficulty (PIGD) motor subtypes remain poorly understood. Our ...