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Assessing multiple MRI sequences in deep learning-based synthetic CT generation for MR-only radiation therapy of head and neck cancers.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: This study investigated the effect of multiple magnetic resonance (MR) sequences on the quality of deep-learning-based synthetic computed tomography (sCT) generation in the head and neck region.

Unveiling NLR pathway signatures: EP300 and CPN60 markers integrated with clinical data and machine learning for precision NASH diagnosis.

Cytokine
BACKGROUND: Given the increasing prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) and non-alcoholic steatohepatitis (NASH), there is a critical need for accurate non-invasive early diagnostic markers.

Explainable AI-driven scalogram analysis and optimized transfer learning for sleep apnea detection with single-lead electrocardiograms.

Computers in biology and medicine
Sleep apnea, a fatal sleep disorder causing repetitive respiratory cessation, requires immediate intervention due to neuropsychological issues. However, existing approaches such as polysomnography, considered the most reliable and accurate test to de...

Discovering Vitamin-D-Deficiency-Associated Factors in Korean Adults Using KNHANES Data Based on an Integrated Analysis of Machine Learning and Statistical Techniques.

Nutrients
: Vitamin D deficiency (VDD) is a global health concern associated with metabolic disease and immune dysfunction. Despite known risk factors like limited sun exposure, diet, and lifestyle, few studies have explored these factors comprehensively on a ...

A Novel Deep Learning-Based (3D U-Net Model) Automated Pulmonary Nodule Detection Tool for CT Imaging.

Current oncology (Toronto, Ont.)
BACKGROUND: Precise detection and characterization of pulmonary nodules on computed tomography (CT) is crucial for early diagnosis and management.

Associations between age, red cell distribution width and 180-day and 1-year mortality in giant cell arteritis patients: mediation analyses and machine learning in a cohort study.

Arthritis research & therapy
OBJECTIVE: The aim of this study was to investigate the correlation between age, red cell distribution width (RDW) levels, and 180-day and 1-year mortality in giant cell arteritis (GCA) patients hospitalized or admitted to the ICU.

AI versus human-generated multiple-choice questions for medical education: a cohort study in a high-stakes examination.

BMC medical education
BACKGROUND: The creation of high-quality multiple-choice questions (MCQs) is essential for medical education assessments but is resource-intensive and time-consuming when done by human experts. Large language models (LLMs) like ChatGPT-4o offer a pro...

Unsupervised machine learning clustering approach for hospitalized COVID-19 pneumonia patients.

BMC pulmonary medicine
BACKGROUND: Identification of distinct clinical phenotypes of diseases can guide personalized treatment. This study aimed to classify hospitalized COVID-19 pneumonia subgroups using an unsupervised machine learning approach.

Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients.

Scientific reports
Post-Liver transplantation (LT) survival rates stagnate, with biliary complications (BC) as a major cause of death. We analyzed longitudinal data with a median 19-month follow-up. BC was diagnosed with ultrasounds and MRCP. Missing data was imputed u...

Advancing Alzheimer's disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study.

BMJ open
OBJECTIVES: Alzheimer's disease (AD) poses a significant challenge for individuals aged 65 and older, being the most prevalent form of dementia. Although existing AD risk prediction tools demonstrate high accuracy, their complexity and limited access...