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Identification of Recurrence-associated Gene Signatures and Machine Learning-based Prediction in IDH-Wildtype Histological Glioblastoma.

Journal of molecular neuroscience : MN
Glioblastoma (GBM) is a highly aggressive brain tumor with frequent recurrence, yet the molecular mechanisms driving recurrence remain poorly understood. Identifying recurrence-associated genes may improve prognosis and treatment strategies. We appli...

A dual-branch hybrid network with bilateral-difference awareness for collateral scoring on CT angiography of acute ischemic stroke patients.

Physics in medicine and biology
Acute ischemic stroke (AIS) patients with good collaterals tend to have better outcomes after endovascular therapy. Existing collateral scoring methods rely mainly on vessel segmentation and convolutional neural networks (CNNs), often ignoring bilate...

A method for predicting postpartum depression via an ensemble neural network model.

Frontiers in public health
INTRODUCTION: Postpartum depression (PPD) has numerous adverse impacts on the families of new mothers and society at large. Early identification and intervention are of great significance. Although there are many existing machine learning classifiers...

A retrospective study using machine learning to develop predictive model to identify rotavirus-associated acute gastroenteritis in children.

PeerJ
BACKGROUND: Rotavirus is the leading cause of severe dehydrating diarrhea in children under 5 years worldwide. Timely diagnosis is critical, but access to confirmatory testing is limited in hospital settings. Machine learning (ML) models have shown p...

c-Triadem: A constrained, explainable deep learning model to identify novel biomarkers in Alzheimer's disease.

PloS one
Alzheimer's disease (AD) is a neurodegenerative disorder that requires early diagnosis for effective management. However, issues with currently available diagnostic biomarkers preclude early diagnosis, necessitating the development of alternative bio...

AADNet: Exploring EEG Spatiotemporal Information for Fast and Accurate Orientation and Timbre Detection of Auditory Attention Based on a Cue-Masked Paradigm.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Auditory attention decoding from electroencephalogram (EEG) could infer to which source the user is attending in noisy environments. Decoding algorithms and experimental paradigm designs are crucial for the development of technology in practical appl...

Temporal validation of machine learning models for pre-eclampsia prediction using routinely collected maternal characteristics: A validation study.

Computers in biology and medicine
BACKGROUND: Pre-eclampsia (PE) contributes to more than one-fourth of all maternal deaths and half a million newborn deaths worldwide every year. Early screening and interventions can reduce PE incidence and related complications. We aim to 1) tempor...

Integrating Machine Learning and Bulk and Single-Cell RNA Sequencing to Decipher Diverse Cell Death Patterns for Predicting the Prognosis of Neoadjuvant Chemotherapy in Breast Cancer.

International journal of molecular sciences
Breast cancer (BRCA) continues to pose a serious risk to women's health worldwide. Neoadjuvant chemotherapy (NAC) is a critical treatment strategy. Nevertheless, the heterogeneity in treatment outcomes necessitates the identification of reliable biom...

Machine learning models for improving the diagnosing efficiency of skeletal class I and III in German orthodontic patients.

Scientific reports
The precise and efficient diagnosis of an individual's skeletal class is necessary in orthodontics to ensure correct and stable treatment planning. However, it is difficult to efficiently determine the true skeletal class due to several correlations ...

Deep learning enabled liquid-based cytology model for cervical precancer and cancer detection.

Nature communications
Deep learning (DL) enabled liquid-based cytology has potential for cervical cancer screening or triage. Here, we develop a DL model using whole cytology slides from 17,397 women and test it on 10,826 additional cases through a three-stage process. Th...