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Characterizing immune profiles in hepatocellular carcinoma patients benefiting from pembrolizumab and lenvatinib using machine learning.

BMC cancer
BACKGROUND: Combination immunotherapies, such as pembrolizumab plus lenvatinib (PL), are commonly used in treatment for unresectable hepatocellular carcinoma (uHCC). However, it remains challenging to predict which patients will benefit from this the...

Dual-task walking for early detection of Alzheimer's disease: comparative analysis of tasks using whole-body gait variables.

BMC geriatrics
BACKGROUND: The worldwide rise in dementia creates an urgent need for screening methods that are both sensitive and easy to administer. Dual-task walking-requiring people to walk while performing a second cognitive or motor task-meets these criteria ...

MobileDANet integrating transfer learning and dynamic attention for classifying multi target histopathology images with explainable AI.

Scientific reports
Cancer is a life-threatening disease that affects several human lives all over the world. The classification of cancer severities utilizing histopathological images is vital for effective and timely diagnosis. This always creates a demandable require...

Prediction of advanced chronic kidney disease through retinal fundus images by deep learning.

Scientific reports
This study was developed and evaluated deep learning model for detecting chronic kidney disease (CKD) by retinal fundus images. This study included 42,963 clinical visits from 17,442 patients who underwent retinal fundus examination between October 1...

Artificial intelligence for predicting depression anxiety and stress using psychometric data.

Scientific reports
Mental health is a crucial aspect of overall well-being, yet it is often overlooked due to stigma and limited accessibility to care. This study investigates the ability of artificial intelligence (AI) to predict common psychological conditions, depre...

Cervical cancer prediction using deformable kernel darknet-53 and depth wise separable convolutional neural networks.

Scientific reports
The prediction of Cervical Cancer (CC) remains a tough task due to diverse clinical variations and unbalanced data distribution, while good-quality data remains limited. Early CC signs tend to lack distinct characteristics, which makes their precise ...

Reducing annotation burden in physical activity research using vision language models.

Scientific reports
Data from wearable devices collected in free-living settings, and labelled with physical activity behaviours compatible with health research, are essential for both validating existing wearable-based measurement approaches and developing novel machin...

Long-term exposure to ambient air pollution and cardiometabolic multimorbidity in Chinese adults over 45 years.

Scientific reports
The rising prevalence of cardiometabolic multimorbidity (CMM), characterized by the coexistence of two or more cardiometabolic disorders, poses a significant public health challenge in aging populations. While ambient air pollution is a recognized en...

Machine learning for early prediction of secondary cancer after radiotherapy.

Scientific reports
Secondary cancers (SCs) following radiotherapy (RT) represent a significant long-term risk of cancer survivors, necessitating accurate predictive models for early intervention. This study developed a machine learning (ML) model integrating clinical, ...

Modality-projection universal model for comprehensive full-body medical imaging segmentation.

Nature communications
The integration of deep learning in medical imaging has significantly advanced diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to inherent inter-modality variabilit...