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Fluorescence

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FMT-ReconNet: Fluorescence Molecular Tomography Reconstruction using Prior Knowledge and Deformation Neural Network.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Fluorescence molecular tomography (FMT) is a powerful imaging technique for 3D reconstruction of internal fluorescent sources. However, its spatial resolution is limited by a simplified forward model and an ill-posed inverse problem. To address this,...

Performance of image processing analysis and a deep convolutional neural network for the classification of oral cancer in fluorescence visualization.

International journal of oral and maxillofacial surgery
The aim of this prospective study was to determine the effectiveness of screening using image processing analysis and a deep convolutional neural network (DCNN) to classify oral cancers using non-invasive fluorescence visualization. The study include...

Deep Learning-Assisted Fluorescence Single-Particle Detection of Fumonisin B Powered by Entropy-Driven Catalysis and Argonaute.

Analytical chemistry
Timely and accurate detection of trace mycotoxins in agricultural products and food is significant for ensuring food safety and public health. Herein, a deep learning-assisted and entropy-driven catalysis (EDC)-Argonaute powered fluorescence single-p...

Fluorescence Lifetime Endoscopy with a Nanosecond Time-Gated CAPS Camera with IRF-Free Deep Learning Method.

Sensors (Basel, Switzerland)
Fluorescence imaging has been widely used in fields like (pre)clinical imaging and other domains. With advancements in imaging technology and new fluorescent labels, fluorescence lifetime imaging is gradually gaining recognition. Our research departm...

Deep-Learning-Assisted Digital Fluorescence Immunoassay on Magnetic Beads for Ultrasensitive Determination of Protein Biomarkers.

Analytical chemistry
Digital fluorescence immunoassay (DFI) based on random dispersion magnetic beads (MBs) is one of the powerful methods for ultrasensitive determination of protein biomarkers. However, in the DFI, improving the limit of detection (LOD) is challenging s...

Machine learning-assisted washing-free detection of extracellular vesicles by target recycling amplification based fluorescent aptasensor for accurate diagnosis of gastric cancer.

Talanta
Extracellular vesicles (EVs) are promising non-invasive biomarkers for cancer diagnosis. EVs proteins play a critical role in tumor progress and metastasis. However, accurately and reliably diagnosing cancers is greatly limited by single protein mark...

A multimodal deep learning model for detecting endoscopic images of near-infrared fluorescence capsules.

Biosensors & bioelectronics
Early screening for gastrointestinal (GI) diseases is critical for preventing cancer development. With the rapid advancement of deep learning technology, artificial intelligence (AI) has become increasingly prominent in the early detection of GI dise...

Emerging applications of fluorescence excitation-emission matrix with machine learning for water quality monitoring: A systematic review.

Water research
Fluorescence excitation-emission matrix (FEEM) spectroscopy is increasingly utilized in water quality monitoring due to its rapid, sensitive, and non-destructive measurement capabilities. The integration of machine learning (ML) techniques with FEEM ...

Machine learning enables high-throughput, low-replicate screening for novel anti-seizure targets and compounds using combined movement and calcium fluorescence in larval zebrafish.

European journal of pharmacology
Identifying new anti-seizure medications (ASMs) is difficult due to limitations in animal-based assays. Zebrafish (Danio rerio) serve as a model for chemical and genetic seizures, but current methods for detecting anti-seizure responses are limited b...

Fluorescent sensor array for rapid bacterial identification using antimicrobial peptide-functionalized gold nanoclusters and machine learning.

Talanta
Bacterial infectious diseases pose significant challenges to public health, emphasizing the need for rapid and accurate diagnostic tools. Here, we introduced a multichannel fluorescent sensor array based on antimicrobial peptide-functionalized gold n...