AIMC Topic: Gastrointestinal Microbiome

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Predicting host health status through an integrated machine learning framework: insights from healthy gut microbiome aging trajectory.

Scientific reports
The gut microbiome, recognized as a critical component in the development of chronic diseases and aging processes, constitutes a promising approach for predicting host health status. Previous research has underscored the potential of microbiome-based...

Effects of immersion bathing in Lactobacillus plantarum CLY-05 on the growth performance, non-specific immune enzyme activities and gut microbiota of Apostichopus japonicus.

PloS one
In order to study the optimal use of Lactobacillus plantarum in sea cucumber (Apostichopus japonicus), 49 days feeding trial was conducted to determine the influence of immersion bathing in different concentrations of Lactobacillus plantarum CLY-05 o...

Unraveling Microplastic Effects on Gut Microbiota across Various Animals Using Machine Learning.

ACS nano
Microplastics, rapidly expanding and durable pollutant, have been shown to significantly impact gut microbiota across a spectrum of animal species. However, comprehensive analyses comparing microplastic effects on gut microbiota among these species a...

Understanding Parkinson's: The microbiome and machine learning approach.

Maturitas
OBJECTIVE: Given that Parkinson's disease is a progressive disorder, with symptoms that worsen over time, our goal is to enhance the diagnosis of Parkinson's disease by utilizing machine learning techniques and microbiome analysis. The primary object...

Faecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients.

Gut microbes
The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined the crosstalk between gut microbiome, diet, gut healt...

Machine learning analysis of sex and menopausal differences in the gut microbiome in the HELIUS study.

NPJ biofilms and microbiomes
Sex differences in the gut microbiome have been examined previously, but results are inconsistent, often due to small sample sizes. We investigated sex and menopausal differences in the gut microbiome in a large multi-ethnic population cohort study, ...

Unravelling metabolite-microbiome interactions in inflammatory bowel disease through AI and interaction-based modelling.

Biochimica et biophysica acta. Molecular basis of disease
Inflammatory Bowel Diseases (IBDs) are chronic inflammatory disorders of the gastrointestinal tract and colon affecting approximately 7 million individuals worldwide. The knowledge of specific pathology and aetiological mechanisms leading to IBD is l...

Targeted isolation and AI-based analysis of edible fungal polysaccharides: Emphasizing tumor immunological mechanisms and future prospects as mycomedicines.

International journal of biological macromolecules
Edible fungal polysaccharides have emerged as significant bioactive compounds with diverse therapeutic potentials, including notable anti-tumor effects. Derived from various fungal sources, these polysaccharides exhibit complex biological activities ...