AIMC Topic: Gastrointestinal Microbiome
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Deep learning-based differential gut flora for prediction of Parkinson's.
PloS one
Jan 7, 2025
BACKGROUND: There had been extensive research on the role of the gut microbiota in human health and disease. Increasing evidence suggested that the gut-brain axis played a crucial role in Parkinson's disease, with changes in the gut microbiota specul...
Understanding the role of the gut microbiome in solid tumor responses to immune checkpoint inhibitors for personalized therapeutic strategies: a review.
Frontiers in immunology
Jan 7, 2025
Immunotherapy, especially immune checkpoint inhibitor (ICI) therapy, has yielded remarkable outcomes for some patients with solid cancers, but others do not respond to these treatments. Recent research has identified the gut microbiota as a key modul...
Effects of data transformation and model selection on feature importance in microbiome classification data.
Microbiome
Jan 4, 2025
BACKGROUND: Accurate classification of host phenotypes from microbiome data is crucial for advancing microbiome-based therapies, with machine learning offering effective solutions. However, the complexity of the gut microbiome, data sparsity, composi...
Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution.
Frontiers in cellular and infection microbiology
Jan 3, 2025
BACKGROUND: Yin-deficiency constitution (YinDC) refers to a traditional Chinese medicine concept, characterized by an imbalance state that includes an imbalance in the gut microbiota, resulting from a relative deficiency of Yin fluids within the body...
Predicting host health status through an integrated machine learning framework: insights from healthy gut microbiome aging trajectory.
Scientific reports
Dec 28, 2024
The gut microbiome, recognized as a critical component in the development of chronic diseases and aging processes, constitutes a promising approach for predicting host health status. Previous research has underscored the potential of microbiome-based...
Effects of immersion bathing in Lactobacillus plantarum CLY-05 on the growth performance, non-specific immune enzyme activities and gut microbiota of Apostichopus japonicus.
PloS one
Dec 27, 2024
In order to study the optimal use of Lactobacillus plantarum in sea cucumber (Apostichopus japonicus), 49 days feeding trial was conducted to determine the influence of immersion bathing in different concentrations of Lactobacillus plantarum CLY-05 o...
Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial (phase II).
PloS one
Dec 27, 2024
BACKGROUND: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diar...
Unraveling Microplastic Effects on Gut Microbiota across Various Animals Using Machine Learning.
ACS nano
Dec 26, 2024
Microplastics, rapidly expanding and durable pollutant, have been shown to significantly impact gut microbiota across a spectrum of animal species. However, comprehensive analyses comparing microplastic effects on gut microbiota among these species a...
Understanding Parkinson's: The microbiome and machine learning approach.
Maturitas
Dec 23, 2024
OBJECTIVE: Given that Parkinson's disease is a progressive disorder, with symptoms that worsen over time, our goal is to enhance the diagnosis of Parkinson's disease by utilizing machine learning techniques and microbiome analysis. The primary object...
Machine learning analysis of sex and menopausal differences in the gut microbiome in the HELIUS study.
NPJ biofilms and microbiomes
Dec 19, 2024
Sex differences in the gut microbiome have been examined previously, but results are inconsistent, often due to small sample sizes. We investigated sex and menopausal differences in the gut microbiome in a large multi-ethnic population cohort study, ...
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