AIMC Topic: Head and Neck Neoplasms

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Development and validation of MRI-derived deep learning score for non-invasive prediction of PD-L1 expression and prognostic stratification in head and neck squamous cell carcinoma.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Immunotherapy has revolutionized the treatment landscape for head and neck squamous cell carcinoma (HNSCC) and PD-L1 combined positivity score (CPS) scoring is recommended as a biomarker for immunotherapy. Therefore, this study aimed to d...

New Perspectives and State of the Art in Interventional Radiotherapy (Brachytherapy) for Head and Neck Tumors.

Magyar onkologia
AIM: This review aims to evaluate the role of interventional radiotherapy (IRT - brachytherapy) in the clinical management of head and neck (H&N) cancers, focusing on recent technological advancements and their impact on clinical outcomes.

Novel pre-spatial data fusion deep learning approach for multimodal volumetric outcome prediction models in radiotherapy.

Medical physics
BACKGROUND: Given the recent increased emphasis on multimodal neural networks to solve complex modeling tasks, the problem of outcome prediction for a course of treatment can be framed as fundamentally multimodal in nature. A patient's response to tr...

Assessing multiple MRI sequences in deep learning-based synthetic CT generation for MR-only radiation therapy of head and neck cancers.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: This study investigated the effect of multiple magnetic resonance (MR) sequences on the quality of deep-learning-based synthetic computed tomography (sCT) generation in the head and neck region.

Multiple machine learning-based integrations of multi-omics data to identify molecular subtypes and construct a prognostic model for HNSCC.

Hereditas
BACKGROUND: Immunotherapy has introduced new breakthroughs in improving the survival of head and neck squamous cell carcinoma (HNSCC) patients, yet drug resistance remains a critical challenge. Developing personalized treatment strategies based on th...

A comparison of different machine learning classifiers in predicting xerostomia and sticky saliva due to head and neck radiotherapy using a multi-objective, multimodal radiomics model.

Biomedical physics & engineering express
. Although radiotherapy techniques are a primary treatment for head and neck cancer (HNC), they are still associated with substantial toxicity and side effects. Machine learning (ML) based radiomics models for predicting toxicity mostly rely on featu...

An Information Fusion System-Driven Deep Neural Networks With Application to Cancer Mortality Risk Estimate.

IEEE transactions on neural networks and learning systems
Next-generation sequencing (NGS) genomic data offer valuable high-throughput genomic information for computational applications in medicine. Using genomic data to identify disease-associated genes to estimate cancer mortality risk remains challenging...

Automatic cervical lymph nodes detection and segmentation in heterogeneous computed tomography images using deep transfer learning.

Scientific reports
To develop a deep learning model using transfer learning for automatic detection and segmentation of neck lymph nodes (LNs) in computed tomography (CT) images, the study included 11,013 annotated LNs with a short-axis diameter ≥ 3 mm from 626 head an...

TransAnaNet: Transformer-based anatomy change prediction network for head and neck cancer radiotherapy.

Medical physics
BACKGROUND: Adaptive radiotherapy (ART) can compensate for the dosimetric impact of anatomic change during radiotherapy of head-neck cancer (HNC) patients. However, implementing ART universally poses challenges in clinical workflow and resource alloc...

Automating the optimization of proton PBS treatment planning for head and neck cancers using policy gradient-based deep reinforcement learning.

Medical physics
BACKGROUND: Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of potentially conflicting planning objectives are involved. Deep reinforcement le...