The perception and production of regular geometric shapes, a characteristic trait of human cultures since prehistory, has unknown neural mechanisms. Behavioral studies suggest that humans are attuned to discrete regularities such as symmetries and pa...
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Jan 12, 2026
BACKGROUND: Distinguishing dangerous from benign vertigo remains a diagnostic challenge. Our study aimed to develop and evaluate a machine learning model to differentiate between dangerous and benign vertigo in the outpatient setting across two medic...
Irritable bowel syndrome (IBS), a disorder of gut-brain interaction, is diagnosed using symptom-based Rome criteria. These criteria classify IBS patients into four subtypes in accordance to their stool patterns. However, whether this subtyping approa...
Air pollution caused by suspended particulate matter (PM) remains one of the key environmental challenges in Poland, particularly in the context of public health and spatial planning. This study presents a spatio-temporal analysis based on data from ...
The thumb plays a crucial role in hand function, yet its proprioceptive abilities remain poorly understood. Here we quantified dynamic thumb localization ability, as well as how this ability adapts to a perturbation, in unimpaired participants. For t...
The viscosity of monoclonal antibody solutions is critical in their biopharmaceutical application, as it directly influences the ease of subcutaneous injection. Although many descriptors have been developed to enable the prediction of viscosity, the...
Journal of computer-aided molecular design
Jan 10, 2026
A prodrug is a pharmacologically inactive (or attenuated) derivative that undergoes bioreversible transformation in vivo to release an active parent drug, enabling temporary optimization of properties such as solubility, permeability, and targeting. ...
Apoptosis : an international journal on programmed cell death
Jan 10, 2026
Autism spectrum disorder (ASD) involves neuroinflammation and dysregulated neuronal death but lacks objective diagnostic biomarkers. This study investigated whether cell death could serve as a molecular basis for ASD diagnosis. We identified cell dea...
Medical science monitor : international medical journal of experimental and clinical research
Jan 10, 2026
BACKGROUND Diabetes is increasingly prevalent among older adults; mild cognitive impairment (MCI) comorbidity in this group represents a major concern. Existing MCI prediction methods are often inaccurate, but machine learning (ML) offers improved po...
The study is aimed at exploring the potential of using ChatGPT-4 to develop multiple-choice questions that adhere to item development principles through the application of reverse engineering techniques in nursing education. To determine whether Chat...
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