AIMC Topic: Humans

Clear Filters Showing 2261 to 2270 of 95995 articles

Rebuilding the gut ecosystem: Emerging strategies targeting the microbiota in antibiotic-associated diarrhea.

Acta microbiologica et immunologica Hungarica
Antibiotic-associated diarrhea (AAD) is a prevalent iatrogenic complication of antibiotic therapy, primarily triggered by dysbiosis and loss of intestinal homeostasis. The traditional interventions, such as empirical probiotic use, have shown a modes...

Aging as an active player in Alzheimer's disease classification: Insights from feature selection in BrainAge models.

NeuroImage
BACKGROUND: BrainAge models estimate the biological age of the brain using neuroimaging or clinical features, making them promising tools for studying neurodegenerative diseases like Alzheimer's disease. However, the reliance of BrainAge models on ne...

Machine learning and multi-omics integration reveal TRPV2 as a central regulator in bicuspid aortic valve calcification.

Biochemical and biophysical research communications
BACKGROUND: Bicuspid aortic valve (BAV), the most common congenital heart defect, is strongly predisposed to early calcification, yet the molecular drivers remain poorly defined. This study aims to identify the functional role of transient receptor p...

DEHP promotes psoriasis via immune modulation and direct molecular interactions: Evidence from epidemiology, multi-omics, and structural simulation.

The Science of the total environment
Di (2-ethylhexyl) phthalate (DEHP), a widely used plasticizer with known immunotoxic effects, has been suspected of aggravating inflammatory skin conditions, yet its role in autoimmune diseases such as psoriasis remains poorly defined. In this study,...

Methods and Uncertainty in Predictions of Arsenic Exposure and Health Outcomes for Private Well Users in Massachusetts.

Environmental science & technology
In the United States, most people get their drinking water from public water systems, whose quality is regulated by the Safe Drinking Water Act; however, an estimated 40 million people rely on unregulated private wells. In Massachusetts ∼500,000 peop...

Metabolite Identification Data in Drug Discovery, Part 2: Site-of-Metabolism Annotation, Analysis, and Exploration for Machine Learning.

Molecular pharmaceutics
The ability to pinpoint and predict sites of metabolism (SoMs) is essential for designing and optimizing effective and safe bioactive small molecules. However, the number of molecules with annotated SoMs is limited, hindering the advancement of data-...

Assessing User Engagement With an Interactive Mapping Dashboard for Overdose Prevention Informed by Predictive Modeling in Rhode Island.

Journal of public health management and practice : JPHMP
CONTEXT: Predictive modeling can identify neighborhoods at elevated risk of future overdose death and may assist community organizations' decisions about harm reduction resource allocation. In Rhode Island, PROVIDENT is a research initiative and rand...

Interpretability of automated machine learning methods in psychological research: A tutorial with AutoGluon in Python.

Behavior research methods
Integrating artificial intelligence into psychological research represents a significant direction in contemporary psychology. Utilizing supervised and unsupervised machine learning techniques can further aid in understanding the nonlinear relationsh...

Intelligent optimization of track and field teaching using machine learning and wearable sensors.

Scientific reports
Traditional track and field education relies heavily on subjective assessment and manual feedback systems, creating critical barriers to personalized instruction in large-scale educational settings. This study presents a novel machine learning framew...

Clinical application of 3D reconstruction and accurate volume measurement of white matter in patients with cognitive dysfunction.

Scientific reports
To quantitatively measure the volume of white matter hyperintensities (WMHs) in different parts of the brain in patients with different types of cognitive function and analyze the relationship between WMH volume and cognitive function to obtain a thr...