The advancements in neuroscience research and omics technologies generate extensive data for brain-related diseases and disorders that are scattered across various manuscript repositories and databases, potentially hindering global initiatives to adv...
Journal of chemical information and modeling
Sep 26, 2025
While line notation schemes for molecular structure are well developed, they are generally unable to distinguish different conformations of the same molecule. CSMILES, an extension to the ubiquitous line notation scheme, SMILES, has been developed to...
Journal of chemical information and modeling
Sep 26, 2025
The design of novel central nervous system (CNS) drugs presents formidable challenges due to the restrictive nature of the blood-brain barrier, which imposes stringent physicochemical requirements. Recent advances in deep learning, particularly Trans...
Tumor heterogeneity poses a major challenge to the precision treatment of medulloblastoma (MB). Rapid and accurate subtyping tools are urgently needed for informed clinical decision-making. Herein, we demonstrate the utility of Raman spectroscopy (RS...
Osteoporosis is a prevalent metabolic bone disease that frequently remains undiagnosed due to limited access to bone mineral density (BMD) tests, such as Dual-energy X-ray absorptiometry (DXA). To address this issue, recent research explores alternat...
This paper presents a vision transformer-based, context-aware, real-time Indian Sign Language (ISL) conversational agent designed to enhance digital accessibility for India's Deaf and Hard-of-Hearing community within e-governance services. The system...
Cancer is a complex and heterogeneous condition marked by the unchecked growth and dissemination of abnormal cells, posing significant challenges in detection, treatment, and patient care. As one of the leading global causes of death, a deep understa...
As artificial intelligence (AI) technologies become increasingly integrated into education, understanding how they influence learners' engagement is essential for effective pedagogy. This study examines the motivational mechanisms by which Chinese EF...
Speech perception is fundamental for human communication, but its neural basis is not well understood. Furthermore, while modern neural networks (NNs) can accurately recognize speech, whether they effectively model human speech processing remains unc...
Pancreatic cancer is an aggressive disease with a dense fibrotic stroma and is often accompanied by chronic inflammation. Peritumoral inflammation is typically viewed as a reaction to nearby tumor growth. Here, we report that the inflamed pancreatic ...
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