Alzheimer's disease (AD), acknowledged as the leading cause of dementia, is defined by the accumulation of amyloid plaques and neurofibrillary tangles (NFTs) in the brain. This condition presents a significant challenge to global health due to its co...
This study systematically investigates the alterations in electroencephalogram (EEG) microstates in patients with refractory epilepsy(RE) across different seizure stages. A novel EEG microstate analysis framework is proposed to address the limitation...
Cerebral arteriovenous malformation (AVM) is a cerebrovascular disease associated with a risk of intracranial hemorrhage. Currently, most risk prediction models for AVM rupture are based on demographic characteristics and lesion morphology, while qua...
Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant liver cancer with limited treatment options. Recent evidence implicates lactate metabolism as playing a crucial role in tumor progression, but its precise contribution in iCCA remains uncle...
Coronary heart disease (CHD) remains the leading cause of mortality worldwide, disproportionately affecting low- and middle-income countries where diagnostic resources are limited. Traditional statistical models often fail to deliver adequate predict...
The management of blood glucose in hospitalized patients is confined to retrospective interventions, preventing healthcare professionals from predicting patients' blood glucose levels and potential adverse events in advance. This study employs a deep...
OBJECTIVE: Gliomas are among the most common and heterogeneous primary tumours of the central nervous system. Accurate grading is essential for treatment planning and prognosis, yet conventional histopathological approaches are limited by subjectivit...
AIMS: Accurate cancer subtype classification is critical due to variations in tumor progression and prognosis. Traditionally, pathologists classified subtypes manually by examining pathological slides under the microscope. To address increasing workl...
Langmuir : the ACS journal of surfaces and colloids
Dec 25, 2025
Protein adsorption on surfaces is a highly complex process, governed by intricate interactions between protein, surface and surrounding environment. However, accurately predicting protein adsorption amounts and precisely controlling adsorption behavi...
Laser desorption-ionization mass spectrometry (LDI-MS) is prized for its rapidity, simplicity, low sample consumption, and high throughput in metabolic analysis, with great potential as a diagnostic tool. Herein, an LDI-MS method with sulfone-contain...
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