BACKGROUND: Pyroptosis plays a pivotal role in the pathogenesis of Heart Failure (HF). However, the current understanding of how pyroptosis-related genes (PRGs) influence HF is scarce. This study aimed to explore the link between PRGs and HF based on...
Scandinavian journal of trauma, resuscitation and emergency medicine
Jul 14, 2025
Point-of-care ultrasound is an emerging technology in prehospital emergency care, covering a wide range of medical and traumatic disease patterns. As an ad-hoc imaging modality, it is performed on-scene and during ground or aeromedical transport, ena...
BACKGROUND: The current Surviving Sepsis Campaign (SSC) guidelines provide recommendations on timing of administering antibiotics in sepsis patients based on probability of sepsis and presence of shock. However, there have been minimal efforts to str...
BMC medical informatics and decision making
Jul 14, 2025
OBJECTIVES: Timely intervention in shock is vital, as delays over one hour greatly increase mortality. This study aims to develop an enhanced machine learning model that improves predictive performance by utilizing self-controlled data and applying f...
BACKGROUND: Missing survey data can threaten the validity and generalizability of findings from longitudinal cohort studies. Respondent characteristics and survey attributes may contribute to patterns of survey non-completion, a form of missing data ...
BACKGROUND: Accurately distinguishing the different molecular subtypes of 2021 World Health Organization (WHO) grade 4 Central Nervous System (CNS) gliomas is highly relevant for prognostic stratification and personalized treatment.
Nanorobotics is catalyzing a paradigm shift in GI surgery by synergizing nanoscale engineering, synthetic biology, and intelligent computation to create a novel frontier in precision medicine. This review critically discusses the most recent experime...
Alzheimer's Disease (AD) and related dementias are significant global health issues characterized by progressive cognitive decline and memory loss. Computer-aided systems can help physicians in the early and accurate detection of AD, enabling timely ...
The 4-1BB receptor, a key member of the tumor necrosis factor receptor (TNFR) family, represents a highly promising target for cancer immunotherapy. In this study, we developed a novel in silico pipeline to design VHH domain antibodies targeting 4-1B...
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