Cyclin-dependent kinase 2 (CDK2) modulates the progression of the cell cycle, and its dysregulation results in unchecked cellular proliferation, establishing it as a pivotal target in oncological therapies. We implemented a comprehensive screening pi...
European journal of cancer (Oxford, England : 1990)
Jul 10, 2025
Quantum technologies present a transformative frontier for oncology, promising significant advancements in diagnostics, treatment precision, and drug discovery. The clinical realization of this potential is fundamentally reliant on mastering quantum ...
How do humans construct mental representations of social hierarchies in the absence of direct interpersonal interactions? In many real-world contexts, humans rely on symbolic rank labels-such as titles or performance ratings-to navigate social hierar...
Artificial intelligence (AI) holds significant potential to transform HIV prevention and treatment through the application of advanced technologies such as machine learning (ML), deep learning (DL), and generative AI (Gen AI). These technologies can ...
Journal of chemical information and modeling
Jul 10, 2025
Proinflammatory peptides (PIPs) play a crucial role in immune response modulation by orchestrating cytokine release and leukocyte recruitment. Accurate identification of PIPs is essential for understanding inflammation-related diseases and developing...
Traditional fluorescence lifetime imaging (FLIM) provides valuable quantitative insights for biomedical and molecular biology research, but often relies on computationally intensive datafitting methods to extract meaningful metrics. To address this l...
Liquid chromatography-mass spectrometry (LC-MS) is a commonly used analytical technique in untargeted metabolomics. However, the diverse chemical and physical properties of metabolites often require the use of several different analytical assays for ...
Scandinavian journal of trauma, resuscitation and emergency medicine
Jul 10, 2025
BACKGROUND: Studying the physiological response to severe hemorrhage remains challenging in real-world patients. Animal and human models mitigate some of the challenges by facilitating controlled studies on hemorrhagic shock. Here, we comment on exis...
OBJECTIVE: Emerging evidence suggests a potential relationship between lipid metabolism and idiopathic pulmonary fibrosis (IPF). This study aimed to identify lipid-related genes implicated in IPF pathogenesis.
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