Enzyme inhibition plays a crucial role in drug discovery by governing interactions between molecules and distinct enzymatic sites, facilitating the identification of early drug candidates. However, most nanozymes have been limited to single active si...
Fresh produce packaging (FPP) plays a critical role in protecting fruits and vegetables from various environmental factors. However, the presence, migration, and human health risks of additives in FPP have received limited attention. This study inves...
INTRODUCTION: Epilepsy is a prevalent chronic neurological disorder, with approximately one-third of patients experiencing intractable epilepsy, often necessitating surgical intervention. Deep brain stimulation (DBS) of the thalamus has been introduc...
BACKGROUND: Differentiating major depressive disorder (MDD) from bipolar disorder (BD) remains a significant clinical challenge, as both disorders exhibit overlapping symptoms but require distinct treatment approaches. Advances in voxel-based morphom...
Predicting potential drug-drug interactions (DDIs) from biomedical data plays a critical role in drug therapy, drug development, drug regulation, and public health. However, it remains challenging due to the large number of possible drug combinations...
The increasing demand for population-wide genomic screening and the limited availability of genetic counseling resources have created a pressing need for innovative service delivery models. Chatbots powered by large language models (LLMs) have shown ...
CONTEXT: Targeted drug delivery systems leveraging gold nanoparticles (AuNPs) demand precise atomic-level design to overcome current limitations in drug-loading efficiency and controlled release. Unlike previous focused reviews, this systematic analy...
PURPOSE OF REVIEW: To highlight various preventive and therapeutic strategies via health care delivery system to minimize sight-threatening diabetic retinopathy.
How does genomic information unfold, to give rise to self-constructing living organisms with problem-solving capacities at all levels of organization? We review recent progress that unifies work in developmental genetics and machine learning (ML) to ...
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