AIMC Topic: Humans

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Integrative machine learning identifies robust inflammation-related diagnostic biomarkers and stratifies immune-heterogeneous subtypes in Kawasaki disease.

Pediatric rheumatology online journal
BACKGROUND: Kawasaki disease (KD), a pediatric systemic vasculitis, lacks reliable diagnostic biomarkers and exhibits immune heterogeneity, complicating clinical management. Current therapies face challenges in targeting specific immune pathways and ...

Segmentation of airways and soft tissues on panoramic radiographs using artificial intelligence technology.

BMC oral health
BACKGROUND: Segmentation of airways and soft tissues on panoramic radiographs is a challenging yet crucial task in dental diagnostics, as these regions can often be confused with fractures or other lesions due to superimposition. This study aimed to ...

Using machine learning to identify Parkinson's disease severity subtypes with multimodal data.

Journal of neuroengineering and rehabilitation
BACKGROUND: Classifying and predicting Parkinson's disease (PD) is challenging because of its diverse subtypes based on severity levels. Currently, identifying objective biomarkers associated with disease severity that can distinguish PD subtypes in ...

Assessing medical students' readiness for artificial intelligence after pre-clinical training.

BMC medical education
BACKGROUND: Artificial intelligence (AI) is becoming increasingly relevant in healthcare, necessitating healthcare professionals' proficiency in its use. Medical students and practitioners require fundamental understanding and skills development to m...

AI-Powered early warning systems for clinical deterioration significantly improve patient outcomes: a meta-analysis.

BMC medical informatics and decision making
BACKGROUND: Clinical deterioration is often preceded by subtle physiological changes that, if unheeded, can lead to adverse patient outcomes. The precision of traditional scoring systems in detecting these precursors has limitations, prompting the ex...

Machine-learning model for predicting left atrial thrombus in patients with paroxysmal atrial fibrillation.

BMC cardiovascular disorders
OBJECTIVE: Left atrial thrombus (LAT) poses a significant risk for stroke and other thromboembolic complication in patients with atrial fibrillation (AF). This study aimed to evaluate the incidence and predictors of LAT in patients with paroxysmal AF...

Development of a neural network-based risk prediction model for mild cognitive impairment in older adults with functional disability.

BMC public health
BACKGROUND: Mild Cognitive Impairment (MCI) is a critical transitional stage between normal aging and Alzheimer's disease, and its early identification is essential for delaying disease progression.

SC2Spa: a deep learning based approach to map transcriptome to spatial origins at cellular resolution.

BMC bioinformatics
BACKGROUND: Understanding cellular heterogeneity within tissues hinges on knowledge of their spatial context. However, it is still challenging to accurately map cells to their spatial coordinates.

Evaluating the Impact of AI-Based Model-Informed Drug Development (MIDD): A Comparative Review.

The AAPS journal
Model-informed drug development (MIDD) methods play critical role to ensure development of efficacious, and safe individualized therapies. The application of artificial intelligence/machine learning (AI/ML) within the field of drug development has ex...

Computational approaches in drug chemistry leveraging python powered QSPR study of antimalaria compounds by using artificial neural networks.

Scientific reports
The application of Machine Learning has become a revolutionary instrument in the domain of pharmaceutical research. Machine learning enables the modelling of Quantitative Structure Property Relationship, a crucial task in forecasting the physiochemic...