AIMC Topic: Humans

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Associations among white matter microstructural changes and the development of emotional reactivity and regulation in infancy.

Molecular psychiatry
Deficits in emotional reactivity and regulation assessed in infancy, including high levels of negative emotionality (NE), low positive emotionality (PE) and low soothability, can predict future affective and behavioral disorders. White matter (WM) tr...

Birth weight prediction using artificial intelligence-based placental assessment from macroscopic photo: a retrospective study.

Placenta
BACKGROUND: This study aimed to predict newborn birth weight through multifactorial analysis of macroscopic placental images using artificial intelligence (AI).

Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network.

Cell
In humans, selective and promiscuous interactions between 46 secreted chemokine ligands and 23 cell surface chemokine receptors of the G-protein-coupled receptor (GPCR) family form a complex network to coordinate cell migration. While chemokines and ...

Dynamic simulation of knee joint mechanics: individualized multi-moment finite element modelling of patellar tendon stress during landing.

Journal of biomechanics
Patellar tendinopathy is prevalent in sports requiring high jumping demands, and understanding the in vivo biomechanical behavior of the patellar tendon (PT) during landing is crucial for developing effective injury prevention and rehabilitation stra...

Feasibility of human ethomic biomarkers for the diagnosis and monitoring of hip osteoarthritis.

Journal of biomechanics
Radiographic imaging is typically used to diagnose osteoarthritis (OA). However, patients would typically be sent for imaging after they present to a physician because of joint pain. By this time, the condition is likely irreversible. This study aims...

Integrating AI for infectious disease prediction: A hybrid ANN-XGBoost model for leishmaniasis in Pakistan.

Acta tropica
Addressing leishmaniasis infection remains a substantial challenge in KP-Pakistan due to the increased infection prevalence. Understanding its spreading tool offerings is a major challenge. We essentially design effective approaches to pinpoint its e...

GDM-BC: Non-invasive body composition dataset for intelligent prediction of Gestational Diabetes Mellitus.

Computers in biology and medicine
Gestational Diabetes Mellitus (GDM) refers to any degree of impaired glucose tolerance with onset or first recognition during pregnancy. As a high-prevalence disease, GDM damages the health of both pregnant women and fetuses in the short and long ter...

Frustration in physiology and molecular medicine.

Molecular aspects of medicine
Molecules provide the ultimate language in terms of which physiology and pathology must be understood. Myriads of proteins participate in elaborate networks of interactions and perform chemical activities coordinating the life of cells. To perform th...

Deciphering disordered regions controlling mRNA decay in high-throughput.

Nature
Intrinsically disordered regions within proteins drive specific molecular functions despite lacking a defined structure. Although disordered regions are integral to controlling mRNA stability and translation, the mechanisms underlying these regulator...

Unsupervised non-small cell lung cancer tumor segmentation using cycled generative adversarial network with similarity-based discriminator.

Journal of applied clinical medical physics
BACKGROUND: Tumor segmentation is crucial for lung disease diagnosis and treatment. Most existing deep learning-based automatic segmentation methods rely on manually annotated data for network training.