AIMC Topic: Humans

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A clinical benchmark of public self-supervised pathology foundation models.

Nature communications
The use of self-supervised learning to train pathology foundation models has increased substantially in the past few years. Notably, several models trained on large quantities of clinical data have been made publicly available in recent months. This ...

Sensitivity of a deep-learning-based breast cancer risk prediction model.

Physics in medicine and biology
When it comes to the implementation of deep-learning based breast cancer risk (BCR) prediction models in clinical settings, it is important to be aware that these models could be sensitive to various factors, especially those arising from the acquisi...

Validation of a machine learning algorithm for identifying infants at risk of hypoxic ischaemic encephalopathy in a large unseen data set.

Archives of disease in childhood. Fetal and neonatal edition
OBJECTIVE: To validate a hypoxic ischaemic encephalopathy (HIE) prediction algorithm to identify infants at risk of HIE immediately after birth using readily available clinical data.

Bioactive structures for inhibitors of polymerase enzyme by artificial intelligence.

Future medicinal chemistry
AIMS: Present new bioactive compounds, created by De novo Drug Design and artificial intelligence (AI), as possible inhibitors of polymerase.

Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks.

Pharmaceutical research
OBJECTIVE: Quantitative systems pharmacology (QSP) is widely used to assess drug effects and toxicity before the drug goes to clinical trial. However, significant manual distillation of the literature is needed in order to construct a QSP model. Para...

Comprehensive molecular analyses of an autoimmune-related gene predictive model and immune infiltrations using machine learning methods in intracranial aneurysma.

Frontiers in immunology
BACKGROUND: Increasing evidence indicates a connection between intracranial aneurysm (intracranial aneurysm, IA) and autoimmune diseases. However, the molecular mechanisms from a genetic perspective remain unclear. This study aims to elucidate the po...

The role and machine learning analysis of mitochondrial autophagy-related gene expression in lung adenocarcinoma.

Frontiers in immunology
OBJECTIVE: Lung adenocarcinoma (LUAD) continues to be a primary cause of cancer-related mortality globally, highlighting the urgent need for novel insights finto its molecular mechanisms. This study aims to investigate the relationship between gene e...

Early prediction of sepsis associated encephalopathy in elderly ICU patients using machine learning models: a retrospective study based on the MIMIC-IV database.

Frontiers in cellular and infection microbiology
BACKGROUND: Sepsis associated encephalopathy (SAE) is prevalent among elderly patients in the ICU and significantly affects patient prognosis. Due to the symptom similarity with other neurological disorders and the absence of specific biomarkers, ear...

[Artificial intelligence and civil liability in cancerology: The breast cancer example].

Gynecologie, obstetrique, fertilite & senologie
For some years now, artificial intelligence has been investing in the field of healthcare, in both technical and clinical disciplines. While this technological advance represents a real opportunity for the doctors of today and tomorrow, the fact rema...

Improved performance of fNIRS-BCI by stacking of deep learning-derived frequency domain features.

PloS one
The functional near-infrared spectroscopy-based brain-computer interface (fNIRS-BCI) systems recognize patterns in brain signals and generate control commands, thereby enabling individuals with motor disabilities to regain autonomy. In this study han...