AIMC Topic: Humans

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Integrated brain connectivity analysis with fMRI, DTI, and sMRI powered by interpretable graph neural networks.

Medical image analysis
Multimodal neuroimaging data modeling has become a widely used approach but confronts considerable challenges due to their heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability necessitate...

Evaluating medical AI systems in dermatology under uncertain ground truth.

Medical image analysis
For safety, medical AI systems undergo thorough evaluations before deployment, validating their predictions against a ground truth which is assumed to be fixed and certain. However, in medical applications, this ground truth is often curated in the f...

MDAL: Modality-difference-based active learning for multimodal medical image analysis via contrastive learning and pointwise mutual information.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Multimodal medical images reveal different characteristics of the same anatomy or lesion, offering significant clinical value. Deep learning has achieved widespread success in medical image analysis with large-scale labeled datasets. However, annotat...

DIPathMamba: A domain-incremental weakly supervised state space model for pathology image segmentation.

Medical image analysis
Accurate segmentation of pathology images plays a crucial role in digital pathology workflow. However, two significant issues exist with the present pathology image segmentation methods: (i) Most fully supervised models rely on dense pixel-level anno...

Integrative Multi-Omics Analysis Reveals Molecular Subtypes of Ovarian Cancer and Constructs Prognostic Models.

Journal of immunotherapy (Hagerstown, Md. : 1997)
Ovarian cancer (OV) remains the most lethal gynecological malignancy. The aim of this study was to identify molecular subtypes of OV through integrative multi-omics analysis and construct machine learning-based prognostic models for predicting the ef...

Exploring 4 generation EGFR inhibitors: A review of clinical outcomes and structural binding insights.

European journal of pharmacology
Epidermal growth factor receptor (EGFR) is a potential target for anticancer therapies and plays a crucial role in cell growth, survival, and metastasis. EGFR gene mutations trigger aberrant signaling, leading to non-small cell lung cancer (NSCLC). T...

Antimicrobial resistance: Linking molecular mechanisms to public health impact.

SLAS discovery : advancing life sciences R & D
BACKGROUND: Antimicrobial resistance (AMR) develops into a worldwide health emergency through genetic and biochemical adaptations which enable microorganisms to resist antimicrobial treatment. β-lactamases (blaNDM, blaKPC) and efflux pumps (MexAB-Opr...

From Silos to Synthesis: A comprehensive review of domain adaptation strategies for multi-source data integration in healthcare.

Computers in biology and medicine
BACKGROUND: The integration of data from diverse sources is not only crucial for addressing data scarcity in health informatics but also enables the use of complementary information from multiple datasets. However, the isolated nature of data collect...

Semantic-consistent diffusion model for unsupervised traumatic brain injury detection and segmentation from computed tomography images.

Medical physics
BACKGROUND: Unsupervised traumatic brain injury (TBI) lesion detection aims to identify and segment abnormal regions, such as cerebral edema and hemorrhages, using only healthy training data. Recent advancements in generative models have achieved suc...

Intelligent control of robotic X-ray devices using a language-promptable digital twin.

International journal of computer assisted radiology and surgery
PURPOSE: Natural language offers a convenient, flexible interface for controlling robotic C-arm X-ray systems, making advanced functionality and controls easily accessible.Please confirm if the author names are presented accurately and in the correct...