AIMC Topic: Humans

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Early diagnosis of transient ischemic attack facilitated by SERS-based artificial intelligence sensors.

Mikrochimica acta
Transient ischemic attack (TIA) serves as a critical early warning sign for ischemic stroke. Its timely identification holds significant clinical value in reducing recurrence risk and improving patient prognosis. However, existing detection methods e...

Modelling the quantum-like dynamics of human reliability ratings in human-AI interactions by interaction-dependent Hamiltonians.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
We are rapidly moving to a future in which our information environment is saturated by artificial intelligence (AI), and humans and AI agents will routinely engage in shared decision making even in conditions of high uncertainty and risk (such as nat...

Automated AI for real-time sperm selection in ICSI: reducing variability and studying the role of sperm in embryo development.

Reproductive biology and endocrinology : RB&E
BACKGROUND: The application of Artificial Intelligence (AI) to sperm selection during Intracytoplasmic Sperm Injection (ICSI) procedures represents one of the most innovative advances in assisted reproductive technology (ART). Traditional sperm selec...

Metaheuristic-optimized generative adversarial network for enhanced sparse-view low-dose CT reconstruction.

Biomedical physics & engineering express
Sparse-view low-dose computed tomography (LDCT) imaging poses difficulties in preserving image quality while reducing radiation exposure. Recent research has focused extensively on artificial intelligence (AI) to reduce artifacts in LDCT. This paper ...

Enabling multiple cellular enumeration applications of a bioparticle sensing platform using machine learning.

Analytical methods : advancing methods and applications
Cellular surface receptors are commonly used as diagnostic and prognostic biomarkers for many infectious diseases. Benchtop clinical instruments, , flow cytometers and fluorescence microscopes are commonly employed for identification and quantificati...

Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes.

Science (New York, N.Y.)
Phenotypic drug screening remains constrained by the vastness of chemical space and the technical challenges of scaling experimental workflows. To overcome these barriers, computational methods have been developed to prioritize compounds, but they re...

Integrated Metabolomics and Lipidomics of Tissue and Serum Reveal Mechanistic Pathways and Lipid Signatures Distinguishing Meningioma Grades.

Journal of proteome research
Meningioma, the most prevalent primary intracranial tumor, presents significant clinical challenges due to unclear molecular mechanisms underlying its progression from low-grade (LG) to high-grade (HG) and lack of grade-specific biomarkers. Here, we ...

Mechanistic Disruption of the TREM2-DAP12 Transmembrane Complex by Alzheimer's Disease Mutations: A Multiscale Simulation Study.

Journal of chemical information and modeling
Triggering receptor expressed on myeloid cell 2 (TREM2) is an immunomodulatory receptor that plays a critical role in microglial activation through its association with the adaptor protein DNAX-activation protein 12 (DAP12). Variants in TREM2 have be...

Prediction of antimicrobial resistance from MALDI-TOF mass spectra using machine learning: a validation study.

Journal of clinical microbiology
UNLABELLED: Matrix-assisted laser desorption-ionization-time of flight (MALDI-TOF) mass spectra can be used to predict antimicrobial resistance (AMR) using machine learning (ML). This study aimed to validate the performance of ML models for AMR predi...

Proximity Effects Leveraged in Ligand-Directed Chemical Labeling of Natural Proteins under Live Conditions.

Accounts of chemical research
ConspectusCovalent chemical labeling of proteins is central to chemical biology, offering functional modifications beyond imaging probes. While genetically engineered systems using self-labeling tags (e.g., HaloTag, SNAP-Tag) or genetic code expansio...