Biomedical physics & engineering express
Dec 3, 2025
Hyperlipidemia detection involves invasive, time-consuming procedures requiring clinical laboratories and blood samples. Often asymptomatic in its early stages, hyperlipidemia significantly increases the risk of cardiovascular diseases. The objective...
BACKGROUND: Hyperlipidemia (HLP) exacerbates myocardial cell injury by impairing lipophagy, a crucial lipid metabolic process, thereby increasing the risk of acute myocardial infarction (AMI). This study aims to identify biomarkers associated with HL...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Apr 22, 2025
BACKGROUND: Dysregulated blood lipid metabolism, a primary driver of hyperlipidemia, is closely associated with excessive very low-density lipoprotein (VLDL) synthesis and secretion. Nuciferine, a bioactive compound isolated from lotus leaves, demons...
Journal of primary care & community health
Apr 16, 2025
BACKGROUND: Artificial intelligence (AI) platforms can potentially enhance clinical decision-making (CDM) in primary care settings. OpenEvidence (OE), an AI tool, draws from trusted sources to generate evidence-based medicine (EBM) recommendations to...
Hyperlipidemia, a major risk factor for cardiovascular diseases, is associated with limitations in clinical lipid-lowering medications. Drug repurposing strategies expedite the research process and mitigate development costs, offering an innovative a...
Hyperlipidemia has many ocular manifestations, the most prevalent being retinal vascular occlusion. Hyperlipidemic lesions and occlusions to the vessels supplying the retina result in permanent blindness, necessitating prompt detection and treatment....
Clinica chimica acta; international journal of clinical chemistry
Apr 12, 2022
BACKGROUND: Serum quality is an important factor in the pre-analytical phase of laboratory analysis. Visual inspection of serum quality (including recognition of hemolysis, icterus, and lipemia) is widely used in clinical laboratories but is time-con...
Hyperlipidemia causes diseases like cardiovascular disease, cancer, Type II Diabetes and Alzheimer's disease. Drugs that specifically target HL associated diseases are required for treatment. 34 KEGG pathways targeted by lipid lowering drugs were use...
BACKGROUND: Low-density lipoprotein cholesterol (LDL-C) is a target for cardiovascular prevention. Contemporary equations for LDL-C estimation have limited accuracy in certain scenarios (high triglycerides [TG], very low LDL-C).
BACKGROUND: Machine learning (ML) has been increasingly used in medicine and neurosurgery. We sought to determine whether ML models can distinguish ruptured from unruptured aneurysms and identify features associated with rupture.
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