Acute myeloid leukemia (AML) is a severe hematological malignancy characterized by high recurrence rates, especially in pediatric patients, highlighting the need for reliable prognostic markers. This study proposes methylation signatures associated w...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
May 5, 2025
PURPOSE: Cisplatin treats many common tumors but causes permanent and debilitating hearing loss (HL). The objective of this study was to develop and externally validate a predictive model of HL in cisplatin-treated children and adolescent cancer surv...
INTRODUCTION: Pneumonia is the leading cause of child morbidity and mortality and accounts for 5.6 million under-five child deaths. Pneumonia has a significant impact on the quality of life, the country's economy, and the survival of children. Theref...
AJNR. American journal of neuroradiology
May 2, 2025
BACKGROUND AND PURPOSE: Privacy concerns, such as identifiable facial features within brain scans, have hindered the availability of pediatric neuroimaging data sets for research. Consequently, pediatric neuroscience research lags adult counterparts,...
IMPORTANCE: Unrecognized deterioration among hospitalized children is associated with a high risk of mortality and morbidity. The current approach to pediatric risk stratification is fragmented, as each hospital unit (emergency, ward, or intensive ca...
OBJECTIVE: To assess patient characteristics and care factors that are associated with correct and incorrect predictions of future care locations (ICU vs. non-ICU) by the Criticality Index-Dynamic (CI-D), with the goal of enhancing the CI-D.
The use of machine learning algorithms and artificial intelligence in medicine has attracted significant interest due to its ability to aid in predicting medical outcomes. This study aimed to evaluate the effectiveness of the random forest algorithm ...
Diabetes mellitus stands out as one of the most prevalent chronic conditions affecting pediatric populations. The escalating incidence of childhood type 1 diabetes (T1D) globally is a matter of increasing concern. Developing an effective model that l...
There is currently a paucity of research on the effects of early life exposure to particulate matter (PM) of various size fractions on pneumonia in preschool-aged children. We explored the connections between antenatal and postnatal exposure to atmos...
BACKGROUND: Congenital heart disease (CHD) affects approximately 1% of newborns and is a leading cause of mortality in early childhood. Despite the importance of early detection, current screening methods, such as pulse oximetry and auscultation, hav...
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