AIMC Topic: Inflammation

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Moderate wine consumption measured using the biomarker urinary tartaric acid concentration decreases inflammatory mediators related to atherosclerosis.

The journal of nutrition, health & aging
OBJECTIVES: Several studies suggest that moderate wine consumption, particularly red wine, may have benefits for cardiovascular health. Red wine contains a variety of bioactive compounds, including polyphenols like phenolic acids, which have demonstr...

Predicting Anti-inflammatory Peptides by Ensemble Machine Learning and Deep Learning.

Journal of chemical information and modeling
Inflammation is a biological response to harmful stimuli, aiding in the maintenance of tissue homeostasis. However, excessive or persistent inflammation can precipitate a myriad of pathological conditions. Although current treatments such as NSAIDs, ...

Anti-inflammatory and antioxidative actions of tacrolimus (FK506) on human microglial HMC3 cell line.

Scandinavian journal of immunology
Microglial cells are indispensable for the normal development and functioning of neurons in the central nervous system, where they play a crucial role in maintaining brain homeostasis by surveilling the microenvironment for signs of injury or stress ...

The water-soluble subfraction from Artemisia argyi alleviates LPS-induced inflammatory responses via multiple pathways and targets in vitro and in vivo.

Journal of ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE: As a traditional Chinese medicine, Artemisia argyi has been used medicinally and eaten for more than 2000 years in China. It is widely reported in treating inflammatory diseases such as eczema, dermatitis, arthritis, a...

Small immunological clocks identified by deep learning and gradient boosting.

Frontiers in immunology
BACKGROUND: The aging process affects all systems of the human body, and the observed increase in inflammatory components affecting the immune system in old age can lead to the development of age-associated diseases and systemic inflammation.

Chronic thromboembolic pulmonary hypertension: realising the potential of multimodal management.

The Lancet. Respiratory medicine
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute pulmonary embolism. Important advances have enabled better understanding, characterisation, and treatment of this condition. Guidelines recommending systematic foll...

Blood-based biomarkers of chronic inflammation.

Expert review of molecular diagnostics
INTRODUCTION: Diseases related to chronic persisting inflammation are amongst the largest sources of morbidity and health costs, yet biomarkers for early diagnosis, prognosis, and treatment response are not sufficiently effective.

Diagnosis of Liver Fibrosis Using Artificial Intelligence: A Systematic Review.

Medicina (Kaunas, Lithuania)
The development of liver fibrosis as a consequence of continuous inflammation represents a turning point in the evolution of chronic liver diseases. The recent developments of artificial intelligence (AI) applications show a high potential for impro...

Dynamics of redox signaling in aging via autophagy, inflammation, and senescence.

Biogerontology
Review paper attempts to explain the dynamic aspects of redox signaling in aging through autophagy, inflammation, and senescence. It begins with ROS source in the cell, then states redox signaling in autophagy, and regulation of autophagy in aging. N...