AIMC Topic: Intensive Care Units, Pediatric

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Performance of the pediatric index of mortality (PIM-3) in a Moroccan PICU: challenges in resource-limited settings.

European journal of pediatrics
UNLABELLED: Prognostic scores such as the Pediatric Index of Mortality (PIM-3) are widely used to estimate mortality risk in PICUs, yet their performance in low- and middle-income countries (LMICs) remains uncertain. We aimed to evaluate the predicti...

Large language model as a clinical decision support tool in the initial management of critically ill children: a pilot evaluation.

European journal of pediatrics
UNLABELLED: Large language models (LLMs) like ChatGPT are being explored as clinical decision support tools, but their reliability in pediatric acute care remains uncertain. This pilot study assessed ChatGPT-4.0's performance in the early management ...

Methods for Addressing Missingness in Electronic Health Record Data for Clinical Prediction Models: Comparative Evaluation.

JMIR medical informatics
BACKGROUND: Missing data are a common challenge in electronic health record (EHR)-based prediction modeling. Traditional imputation methods may not suit prediction or machine learning models, and real-world use requires workflows that are implementab...

Machine learning prediction of mortality in pediatric fungemia using the Candida score.

Scientific reports
Pediatric fungemia in pediatric intensive care units (PICUs) carries high mortality. We evaluated whether the Candida Score, combined with clinical variables, predicts mortality after diagnosis using a prespecified multivariable logistic regression (...

Predicting outcomes in pediatric patients with acute kidney injury: a retrospective single-center cohort study using machine learning models.

BMC medical informatics and decision making
OBJECTIVE: To develop and evaluate machine learning models combined with survival analysis for predicting 7-, 14-, and 28-day mortality in critically ill children with acute kidney injury (AKI), identifying key predictors to guide risk stratification...

Expert-augmented machine learning for predicting extubation readiness in the pediatric intensive care unit.

BMC medical informatics and decision making
BACKGROUND: Determining extubation readiness in pediatric intensive care units (PICU) is challenging. We used expert-augmented machine learning (EAML), a method that combines machine learning with human expert knowledge, to predict successful extubat...

Construction and validation of a pain facial expressions dataset for critically ill children.

Scientific reports
Automatic pain assessment for non-communicative children is in high demand. However, the availability of related training datasets remains limited. This study focuses on creating a large-scale dataset of pain facial expressions specifically for Chine...

A machine learning model to predict intradialytic hypotension in pediatric continuous kidney replacement therapy.

Pediatric nephrology (Berlin, Germany)
BACKGROUND: Intradialytic hypotension (IDH) is associated with mortality in adults undergoing intermittent hemodialysis, but this relationship is unclear in critically ill children receiving continuous kidney replacement therapy (CKRT). We aim to eva...

Development and Validation of an Electronic Health Record-Based, Pediatric Acute Respiratory Distress Syndrome Subphenotype Classifier Model.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
OBJECTIVE: To determine if hyperinflammatory and hypoinflammatory pediatric acute respiratory distress syndrome (PARDS) subphenotypes defined using serum biomarkers can be determined solely from electronic health record (EHR) data using machine learn...

Tailoring ventilation and respiratory management in pediatric critical care: optimizing care with precision medicine.

Current opinion in pediatrics
PURPOSE OF REVIEW: Critically ill children admitted to the intensive care unit frequently need respiratory care to support the lung function. Mechanical ventilation is a complex field with multiples parameters to set. The development of precision med...