Patients with lumbar degenerative disease typically undergo preoperative MRI combined with CT scans, but this approach introduces additional ionizing radiation and examination costs. To compare the effectiveness of MRI-based synthetic CT (sCT) in dis...
Journal of orthopaedic surgery and research
May 27, 2025
Spontaneous resorption of lumbar disk herniation (LDH) presents a promising avenue for the non-surgical management of herniated disks. Here we present a 40-year-old female with severe L5/S1 herniation who experienced spontaneous resorption confirmed ...
INTRODUCTION: Aging is characterized by gradual structural and functional changes in the body over time, with intervertebral disc degeneration (IVDD) representing a key manifestation of spinal aging and a major contributor to low back pain (LBP).
BACKGROUND: Low back pain is the leading cause of disability worldwide with a significant socioeconomic burden; artificial intelligence (AI) has proved to have a great potential in supporting clinical decisions at each stage of the healthcare process...
The degeneration of the intervertebral discs in the lumbar spine is the common cause of neurological and physical dysfunctions and chronic disability of patients, which can be stratified into single-(e.g., disc herniation, prolapse, or bulge) and com...
Apoptosis : an international journal on programmed cell death
Dec 4, 2024
Intervertebral disc degeneration (IVDD) is intricately associated with various forms of programmed cell death (PCD). Identifying key PCD types and associated genes is essential for understanding the molecular mechanisms underlying IVDD and discoverin...
BACKGROUND: Low back pain resulting from intervertebral disc degeneration (IVDD) represents a significant global social problem. There are notable differences in the distribution of lymphatic vessels (LV) in normal and pathological intervertebral dis...
BACKGROUND: Intervertebral disc degeneration (IDD) is widely regarded as the primary contributor to low back pain(LBP). As an immune-privileged organ, upon the onset of IDD, various components of the nucleus pulposus (NP) are exposed to the host's im...
Journal of imaging informatics in medicine
Sep 12, 2024
This study aimed to develop a graph neural network (GNN) for automated three-dimensional (3D) magnetic resonance imaging (MRI) visualization and Pfirrmann grading of intervertebral discs (IVDs), and benchmark it against manual classifications. Lumbar...
Journal of orthopaedic surgery and research
Aug 21, 2024
BACKGROUND: In recent years, deep learning (DL) technology has been increasingly used for the diagnosis and treatment of lumbar intervertebral disc (IVD) degeneration. This study aims to evaluate the performance of DL technology for IVD segmentation ...
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