RATIONALE AND OBJECTIVES: To develop and validate a computed tomography (CT) radiomics-based interpretable machine learning (ML) model for predicting 5-year recurrence-free survival (RFS) in non-metastatic clear cell renal cell carcinoma (ccRCC).
RATIONALE AND OBJECTIVES: The classification of renal cell carcinoma (RCC) histological subtypes plays a crucial role in clinical diagnosis. However, traditional image normalization methods often struggle with discrepancies arising from differences i...
International journal of surgery (London, England)
Mar 28, 2025
BACKGROUND: The assessment of the International Society of Urological Pathology (ISUP) nuclear grade is crucial for the management and treatment of clear cell renal cell carcinoma (ccRCC). This study aimed to explore the value of using integrated mul...
The kidney plays a vital role in maintaining homeostasis, but lifestyle factors and diseases can lead to kidney failures. Early detection of kidney disease is crucial for effective intervention, often challenging due to unnoticeable symptoms in the i...
Anti-angiogenic (AA) therapy is a cornerstone of metastatic clear cell renal cell carcinoma (ccRCC) treatment, but not everyone responds, and predictive biomarkers are lacking. CD31, a marker of vasculature, is insufficient, and the Angioscore, an RN...
European journal of cancer (Oxford, England : 1990)
Mar 15, 2025
BACKGROUND: Decisions on the best available treatment in clinical oncology are based on expert opinions in multidisciplinary cancer conferences (MCC). Artificial intelligence (AI) could increase evidence-based treatment by generating additional treat...
BACKGROUND: This study employed a convolutional neural network (CNN) to analyze computed tomography (CT) scans with the aim of differentiating among renal tumors according to histologic sub-type.
OBJECTIVE: To explore the role of artificial intelligence based augmented reality intraoperative real-time navigation in minimally invasive partial nephrectomy to standardize renal hilum dissection procedures and improve operative efficiency.
Cancer immunology, immunotherapy : CII
Feb 25, 2025
BACKGROUND: The pathogenesis and progression of renal cell carcinoma (RCC) involve complex programmed cell death (PCD) processes. As the powerhouse of the cell, mitochondria can influence cell death mechanisms. However, the prognostic significance of...
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