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Liver Cirrhosis

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Real-World Screening Data for Liver Fibrosis in Psoriasis Patients Treated with Biologics.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is positively associated with the prevalence and severity of psoriasis. The fibrosis-4 (FIB-4) index was developed to predict significant liver fibrosis. Using the FIB-4 ind...

Association between serum endocan levels and organ failure in hospitalized patients with cirrhosis.

PloS one
BACKGROUND & AIMS: Acute-on-chronic liver failure is a syndrome characterized by organ failure and high short-term mortality. The lack of reliable biomarkers for the early detection of acute-on-chronic liver failure is a significant challenge. Endoth...

Exploratory study of extracellular matrix biomarkers for non-invasive liver fibrosis staging: A machine learning approach with XGBoost and explainable AI.

Clinical biochemistry
BACKGROUND: Novel circulating markers for the non-invasive staging of chronic liver disease (CLD) are in high demand. Although underutilized, extracellular matrix (ECM) components offer significant diagnostic potential. This study evaluates ECM-relat...

Liver fibrosis stage classification in stacked microvascular images based on deep learning.

BMC medical imaging
BACKGROUND: Monitoring fibrosis in patients with chronic liver disease (CLD) is an important management strategy. We have already reported a novel stacked microvascular imaging (SMVI) technique and an examiner scoring evaluation method to improve fib...

Noninvasive diagnosis of significant liver fibrosis in patients with chronic hepatitis B using nomogram and machine learning models.

Scientific reports
This study aims to construct and validate noninvasive diagnosis models for evaluating significant liver fibrosis in patients with chronic hepatitis B (CHB). A cohort of 259 CHB patients were selected as research subjects. Through random grouping, 182...

Fibrosis and inflammatory activity diagnosis of chronic hepatitis C based on extreme learning machine.

Scientific reports
The traditional diagnosis of chronic hepatitis C usually relies on liver biopsy. Diagnosing chronic hepatitis C based on serum indices provides a non-invasive way to determine the stage of chronic hepatitis C without liver biopsy. In this paper, we p...