AIMC Topic: Liver Cirrhosis

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Development and validation of a machine learning-based prediction model for hepatorenal syndrome in liver cirrhosis patients using MIMIC-IV and eICU databases.

Scientific reports
Hepatorenal syndrome (HRS) is a key contributor to poor prognosis in liver cirrhosis. This study aims to leverage the database to build a predictive model for early identification of high-risk patients. From two sizable public databases, we retrieved...

Golgi protein 73: charting new territories in diagnosing significant fibrosis in MASLD: a prospective cross-sectional study.

Frontiers in endocrinology
OBJECTIVES: To explore the correlation between serum Golgi protein 73 (GP73) levels and the degree of fibrosis in Metabolic dysfunction associated steatotic liver disease (MASLD); to establish a non-invasive diagnostic algorithm based on serum GP73 a...

Multi-site, multi-vendor development and validation of a deep learning model for liver stiffness prediction using abdominal biparametric MRI.

European radiology
BACKGROUND: Chronic liver disease (CLD) is a substantial cause of morbidity and mortality worldwide. Liver stiffness, as measured by MR elastography (MRE), is well-accepted as a surrogate marker of liver fibrosis.

Liver fibrosis stage classification in stacked microvascular images based on deep learning.

BMC medical imaging
BACKGROUND: Monitoring fibrosis in patients with chronic liver disease (CLD) is an important management strategy. We have already reported a novel stacked microvascular imaging (SMVI) technique and an examiner scoring evaluation method to improve fib...

Noninvasive diagnosis of significant liver fibrosis in patients with chronic hepatitis B using nomogram and machine learning models.

Scientific reports
This study aims to construct and validate noninvasive diagnosis models for evaluating significant liver fibrosis in patients with chronic hepatitis B (CHB). A cohort of 259 CHB patients were selected as research subjects. Through random grouping, 182...

Fibrosis and inflammatory activity diagnosis of chronic hepatitis C based on extreme learning machine.

Scientific reports
The traditional diagnosis of chronic hepatitis C usually relies on liver biopsy. Diagnosing chronic hepatitis C based on serum indices provides a non-invasive way to determine the stage of chronic hepatitis C without liver biopsy. In this paper, we p...

Association between serum endocan levels and organ failure in hospitalized patients with cirrhosis.

PloS one
BACKGROUND & AIMS: Acute-on-chronic liver failure is a syndrome characterized by organ failure and high short-term mortality. The lack of reliable biomarkers for the early detection of acute-on-chronic liver failure is a significant challenge. Endoth...