AIMC Topic: Lung Neoplasms

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Towards radiologist-level cancer risk assessment in CT lung screening using deep learning.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
PURPOSE: Lung cancer is the leading cause of cancer mortality in the US, responsible for more deaths than breast, prostate, colon and pancreas cancer combined and large population studies have indicated that low-dose computed tomography (CT) screenin...

Automated detection of lung nodules and coronary artery calcium using artificial intelligence on low-dose CT scans for lung cancer screening: accuracy and prognostic value.

BMC medicine
BACKGROUND: Artificial intelligence (AI) in diagnostic radiology is undergoing rapid development. Its potential utility to improve diagnostic performance for cardiopulmonary events is widely recognized, but the accuracy and precision have yet to be d...

Computer-aided diagnosis of ground glass pulmonary nodule by fusing deep learning and radiomics features.

Physics in medicine and biology
OBJECTIVES: This study aims to develop a computer-aided diagnosis (CADx) scheme to classify between benign and malignant ground glass nodules (GGNs), and fuse deep leaning and radiomics imaging features to improve the classification performance.

Data-efficient and weakly supervised computational pathology on whole-slide images.

Nature biomedical engineering
Deep-learning methods for computational pathology require either manual annotation of gigapixel whole-slide images (WSIs) or large datasets of WSIs with slide-level labels and typically suffer from poor domain adaptation and interpretability. Here we...

Assessment of an Exhaled Breath Test Using High-Pressure Photon Ionization Time-of-Flight Mass Spectrometry to Detect Lung Cancer.

JAMA network open
IMPORTANCE: Exhaled breath is an attractive option for cancer detection. A sensitive and reliable breath test has the potential to greatly facilitate diagnoses and therapeutic monitoring of lung cancer.

Novel gene signatures for stage classification of the squamous cell carcinoma of the lung.

Scientific reports
The squamous cell carcinoma of the lung (SCLC) is one of the most common types of lung cancer. As GLOBOCAN reported in 2018, lung cancer was the first cause of death and new cases by cancer worldwide. Typically, diagnosis is made in the later stages ...

Computer-Aided Diagnosis Research of a Lung Tumor Based on a Deep Convolutional Neural Network and Global Features.

BioMed research international
Based on the better generalization ability and the feature learning ability of the deep convolutional neural network, it is very significant to use the DCNN on the computer-aided diagnosis of a lung tumor. Firstly, a deep convolutional neural network...

Development and Validation of Machine Learning-based Model for the Prediction of Malignancy in Multiple Pulmonary Nodules: Analysis from Multicentric Cohorts.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Nodule evaluation is challenging and critical to diagnose multiple pulmonary nodules (MPNs). We aimed to develop and validate a machine learning-based model to estimate the malignant probability of MPNs to guide decision-making.

A comparison between deep learning convolutional neural networks and radiologists in the differentiation of benign and malignant thyroid nodules on CT images.

Endokrynologia Polska
INTRODUCTION: We designed 5 convolutional neural network (CNN) models and ensemble models to differentiate malignant and benign thyroid nodules on CT, and compared the diagnostic performance of CNN models with that of radiologists.

An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning.

Nature communications
Deep learning for digital pathology is hindered by the extremely high spatial resolution of whole-slide images (WSIs). Most studies have employed patch-based methods, which often require detailed annotation of image patches. This typically involves l...