AIMC Topic: Lung Neoplasms

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HRGCNLDA: Forecasting of lncRNA-disease association based on hierarchical refinement graph convolutional neural network.

Mathematical biosciences and engineering : MBE
Long non-coding RNA (lncRNA) is considered to be a crucial regulator involved in various human biological processes, including the regulation of tumor immune checkpoint proteins. It has great potential as both a cancer biomolecular biomarker and ther...

Real-World Effectiveness of Lung Cancer Screening Using Deep Learning-Based Counterfactual Prediction.

Studies in health technology and informatics
The benefits and harms of lung cancer screening (LCS) for patients in the real-world clinical setting have been argued. Recently, discriminative prediction modeling of lung cancer with stratified risk factors has been developed to investigate the rea...

Weakly Supervised Deep Learning Predicts Immunotherapy Response in Solid Tumors Based on PD-L1 Expression.

Cancer research communications
UNLABELLED: Programmed death-ligand 1 (PD-L1) IHC is the most commonly used biomarker for immunotherapy response. However, quantification of PD-L1 status in pathology slides is challenging. Neither manual quantification nor a computer-based mimicking...

scGraph2Vec: a deep generative model for gene embedding augmented by graph neural network and single-cell omics data.

GigaScience
BACKGROUND: Exploring the cellular processes of genes from the aspects of biological networks is of great interest to understanding the properties of complex diseases and biological systems. Biological networks, such as protein-protein interaction ne...

Meta-Learning on Augmented Gene Expression Profiles for Enhanced Lung Cancer Detection.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex methodolo...

Diagnostic-therapeutic management of pulmonary nodules.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti
BACKGROUND: Lung cancer is one of the leading causes of death worldwide, with incidence and mortality significantly affected by population ageing and changes in the prevalence of risk factors. Lung nodules, which are often detected incidentally on im...

Predicting High-Grade Patterns in Stage I Solid Lung Adenocarcinoma: A Study of 371 Patients Using Refined Radiomics and Deep Learning-Guided CatBoost Classifier.

Technology in cancer research & treatment
INTRODUCTION: This study aimed to devise a diagnostic algorithm, termed the Refined Radiomics and Deep Learning Features-Guided CatBoost Classifier (RRDLC-Classifier), and evaluate its efficacy in predicting pathological high-grade patterns in patien...

A Hybrid 2D Gaussian Filter and Deep Learning Approach with Visualization of Class Activation for Automatic Lung and Colon Cancer Diagnosis.

Technology in cancer research & treatment
Cancer is a significant public health issue due to its high prevalence and lethality, particularly lung and colon cancers, which account for over a quarter of all cancer cases. This study aims to enhance the detection rate of lung and colon cancer by...

[Changes in FDG-PET Images of Small Lung and Liver Masses Caused by the Deep Learning-based Time-of-flight Processing].

Nihon Hoshasen Gijutsu Gakkai zasshi
PURPOSE: The deep learning time-of-flight (DL-ToF) aims to replicate the ToF effects through post-processing, applying deep learning-based enhancement to PET images. This study evaluates the effectiveness of DL-ToF using a chest-abdomen phantom that ...